Sökning: "Chip morphology"

Visar resultat 6 - 10 av 26 avhandlingar innehållade orden Chip morphology.

  1. 6. Mechanisms of Transgene Silencing in Neural Cells -Implications for Ex Vivo Gene Therapy to the Brain

    Författare :Nina Rosenqvist; Neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; Neurologi; Neurology; neuropsychology; ChIP; rat; transgene; insulator; differentiation; GFP; lentivirus; DNA methylation; histone deacetylation; chromatin; expression; silencing; stem cell; progenitor; gene therapy; neurofysiologi; neuropsykologi; CNS; transplantation;

    Sammanfattning : The use of genetically modifi ed neural stem and progenitor cells could possibly be a future strategy for repairing a brain suffering from neurodegeneration. However, so far it has proven diffi cult to maintain sufficient levels of a transferred gene in suitable cell types, after transplantation. LÄS MER

  3. 7. Effects on Machinability due to Microstructure Variations in Case Hardening Steel

    Författare :Karin Björkeborn; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Machinability; Short-term test; Microstructure; Pearlite Nodular Size; Case Hardening Steel; Chip breakability.;

    Sammanfattning : Typical products made of case hardening steel are transmission parts like gear wheels, pinions and crown wheels. Case hardening produces a carbon-rich surface and provides the parts with both enhanced hardness and fatigue life. LÄS MER

  4. 8. Creation of a Nanometer-Scale Toolbox for Molecular Motor Transport-Circuits

    Författare :Richard Bunk; Fasta tillståndets fysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Coating and surface treatment; materialteknik; Materiallära; Material technology; Produktionsteknik; Production technology; Semiconductory physics; Halvledarfysik; Proteins; enzymology; Proteiner; enzymologi; reumatologi; Physics; Fysik; muskelsystem; Skelett; rheumatology locomotion; muscle system; Skeleton; Biofysik; Biophysics; Biomedicinska vetenskaper; Biomedical sciences; fluorescence microscopy; EBL; T-profile channel; nano-imprinting; cargo; quantum dot; silane; myosin; actin; motor protein; factory-on-a-chip; toolbox; lab-on-a-chip; molecular motor; nanotechnology; Biokemisk teknik; Biotechnology; Bioteknik; Skikt och ytbehandling; Biochemical technology;

    Sammanfattning : This thesis presents studies of molecular motors in interaction with nm-scale structures, as well as the development of a set of tools that can be used for the construction of custom-designed nano-transportation systems. In our studies, we have used the latest nanoscale technology and combined this with advanced results from chemistry and biomedical sciences. LÄS MER

  5. 9. Functional Studies of Genes Associated with Muscle Growth in Pigs and Hair Greying in Horses

    Författare :Lin Jiang; Leif Andersson; Kerstin Lindblad-Toh; Gerli Pielberg; Christopher Tuggle; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; QTN; muscle development; IGF2; ZBED6; RNA-seq; ChIP-seq; myoblasts; pancreatic beta cells; Grey horse; melanoma; MITF; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology;

    Sammanfattning : Domestic animals have become very different from their wild ancestors during domestication and animal breeding. This provides a good model to unravel the molecular mechanisms underlying phenotypic variation. In my thesis I have studied genes affecting two important traits, leanness in pigs and hair greying-associated melanoma in horses. LÄS MER

  7. 10. Development of Protein Microarray Chip Technology: An Outlook towards Proteomics and Diagnostics

    Författare :Anton Ressine; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; materialteknik; Materiallära; Material technology; Teknik; Technological sciences; Naturvetenskap; Natural science; Diagnostik; Diagnostics; Medicin människa och djur ; Medicine human and vertebrates ; Biomedicinska vetenskaper; Biomedical sciences; water repellency; superhydrophobicity; proteolitic digestion; MALDI-TOF MS; bioassay; porous silicon; biomarker; diagnostics; protein microarrays; proteomics;

    Sammanfattning : One attractive method for monitoring biomolecular interactions in a highly parallel fashion is the use of microarrays. Microarrays can be applied for screening proteins which makes it an attractive tool in clinical diagnostics, drug discovery studies and basic protein research; even though many methodological challenges and ones relating to the quality control of microarrays still need to be solved. LÄS MER