Sökning: "Neurology"

Visar resultat 1 - 5 av 414 avhandlingar innehållade ordet Neurology.

  1. 1. Curing Multiple Sclerosis How to do it and how to prove it

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Joachim Burman; Jan Fagius; Angelica Loskog; Sara Mangsbo; Paulo Muraro; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomarkers; cerebrospinal fluid; cytokines; hematopoietic stem cell transplantation; immunology; magnetic resonance imaging; multiple sclerosis; neuroimmunology; neurology; Neurology; Neurologi;

    Sammanfattning : Hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment for multiple sclerosis (MS) with now more than 600 documented cases in the medical literature. Long-term remission can be achieved with this therapy, but when is it justified to claim that a patient is cured from MS? In attempt to answer this question, the outcome of the Swedish patients is described, mechanisms behind the therapeutic effect are discussed and new tools for demonstration of absence of disease have been developed. LÄS MER

  2. 2. Synaptic Integration of Hippocampal Neurons Generated in the Adult Brain: Influence of a Pathological Environment

    Detta är en avhandling från Neurology, Lund

    Författare :Katherine Jakubs; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; neurofysiologi; Neurologi; synaptic plasticity; GABA; glutamate; GFP; Neurology; neuropsychology; neurophysiology; hippocampus; dentate gyrus; neurogenesis; LPS; inflammation; epilepsy; SE; patch-clamp;

    Sammanfattning : The adult brain constantly produces new neurons from endogenous neural progenitor cells located in at least two regions, the subgranular zone (SGZ) in dentate gyrus of the hippocampus, and the subventricular zone (SVZ). Major efforts are underway to discover the functional significance of new neurons in the adult brain. LÄS MER

  3. 3. Functional consequences of dopaminergic degeneration : Clinical and experimental studies using a novel stabilizer of dopaminergic systems

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anna Ekesbo; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Parkinson s disease; positron emission tomography; 6-OHDA; MPTP; dyskinesia; dopaminergic degeneration; - -OSU6162; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; Neurology; neurologi;

    Sammanfattning : Since the introduction of levodopa for the treatment of Parkinson's disease (PD) 30 yearsago, the emergence of motor complications, such as levodopa-induced dyskinesias (LID), hasbeen a major clinical problem in advanced stages of the disease. Clinical and preclinical studieshave revealed a number of functional changes in the dopaminergic system that may be ofimportance for the emergence of LIDs. LÄS MER

  4. 4. On pathophysiological mechanisms in amyothrophic lateral sclerosis

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Eva Grundström; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Amyotrophic lateral sclerosis; ALS; spinal cord; motor neuron; cerebrospinal fluid; CSF; muscle; glial cell line-derived neurotrophic factor; GDNF; brain- derived neurotrophic factor; BDNF; ACh; vesamicol; apoptosis; Bax; Bcl-2; neurodegeneration; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; Neurology; neurologi;

    Sammanfattning : Amyotrophic lateral sclerosis is a fatal, progressive neurodegenerative disease with unknown ethiology. The aim of this study was to increase understanding of the pathophysiological mechanisms of dying motor neurons and wasting muscle tissue in this particular disorder. LÄS MER

  5. 5. Migraine and Stress : An Internet administered Multimodal Behavioral Treatment Intervention

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Kerstin Hedborg; Carin Muhr; Ulla Maria Anderberg; Töres Theorell; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Awakening Cortisol Response; Cognitive Behavioral Treatment; Gender; Hand Massage; Internet; Life Events; Migraine; Multimodal; Personality; Salivary Cortisol; Stress; Stress Marker; Stress Susceptibility; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; Neurology; Neurologi;

    Sammanfattning : Migraine is a disabling neurological disorder with high prevalence, the clinical manifestations of which are highly dependent on stress.The overall theme of the present thesis was to address aspects of stress in migraine. LÄS MER