Sökning: "myosin"

Visar resultat 1 - 5 av 104 avhandlingar innehållade ordet myosin.

  1. 1. Myosin myopathy. A new disease entity

    Författare :Homa Tajsharghi; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Neuromuscular disorders; Myosin myopathy; Myosin heavy chain; Myosin storage myopathy;

    Sammanfattning : By the discovery and characterization of two familial myopathies caused by mutations in myosin heavy chaingenes, we introduce a new entity within the field of neuromuscular disorders: Myosin myopathyThe first myopathy affected a family in western Sweden. Previous linkage analysis had located the gene tochromosome 17p13. LÄS MER

  2. 2. Towards Myosin Powered Lab-on-a-Chip Devices

    Författare :Lasse ten Siethoff; Alf Månsson; Miklos Kellermayer; Linnéuniversitetet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; myosin; actin; molecular motors; lab-on-a-chip; nanobiotechnology; bionanotechnology; diagnostics; nanowires; nanowire arrays; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : Myosins are protein motors that use chemical energy in the form of adenosinetriphosphate to produce force and motion. These molecular motors might be usedto power transportation in Lab-on-a-chip devices where a series of laboratory tasks(e.g. separation, concentration and detection) are performed in one sequence on asmall chip. LÄS MER

  3. 3. Variability and adaptation in the contractile system of smooth muscle

    Författare :Mia Löfgren; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; essential light chain; desmin; shortening velocity; integrin; intermediate filament; hypertrophy; non-muscle myosin; smooth muscle; myosin; heavy chain; Physiology; Fysiologi;

    Sammanfattning : This thesis examines the cellular and molecular mechanisms involved in the large diversity of the contractile properties in smooth muscle. Six studies, I-VI, are included. I: a slow smooth muscle (aorta) has a different nucleotide and phosphate dependence compared to a fast type (taenia coli). LÄS MER

  4. 4. Study the role of patient-specific mutations by genetic disease modeling : From gene to function; A study to understand muscles

    Författare :Martin Dahl-Halvarsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Muscles; Myosin; MYH7; Myosin storage myopathy; Laing early-onset myopathy; Drosophila; TOR1A; DYT1; HCM; heart disease;

    Sammanfattning : Many genetic diseases inherited in a dominant fashion have a complex pathological pattern. TOR1A mediated Dystonia-1 (DYT1) is an example of incomplete penetrance, affecting only a third of the carriers. LÄS MER

  5. 5. Biophysical studies of the actin-myosin motor system and applications in nanoscience

    Författare :Mohammad A. Rahman; Alf Månsson; Kazuhiro Oiwa; Linnéuniversitetet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; myosin II; actin; actomyosin force generating cycle; blebbistatin; in vitro motility assay; actin affinity purification; blocking actin; bionanodevices; proteinase k; SDS; triton X100; surface recycling; engineered myosin motor; programmable gate; biocomputation.; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : The actin-myosin motor system plays important roles in cellular processes. In addition, actin and myosin have been used for developments towards nanotechnological applications in recent years. LÄS MER