Sökning: "biomarker"

Visar resultat 1 - 5 av 480 avhandlingar innehållade ordet biomarker.

  1. 1. Proteomic Analysis of Urinary Bladder Cancer Aiming for Novel Biomarkers

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mårten Lindén; Uppsala universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; urine; APOE; FGB; GAL1; LRG1; POLR1E; SERPINA1; STMN1; TOP2A; biomarker; diagnostic biomarker; prognostic biomarker; predictive biomarker; mass spectrometry; western blot; dot blot; immunohistochemistry; IHC; tissue microarray; TMA; urothelium; antibody; antibody-based; urinblåsecancer; biomarkör; diagnos; prognos; urin; proteomik; masspektrometri; immunohistokemi; antikroppar; Molecular Biology; Molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. LÄS MER

  2. 2. Proteomics in biomarker research Insights into the effects of aging and environment on biological systems

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Hanna Amelina; Stockholms universitet.; [2011]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; proteomics; biomarker; peroxisomes; 2-dimensional gel electrophoresis 2-DE ; mass spectrometry MS ; aging; marine pollution; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi; NATURAL SCIENCES Chemistry Environmental chemistry Environmental toxicology; NATURVETENSKAP Kemi Miljökemi Miljötoxikologi; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi; biokemi; Biochemistry;

    Sammanfattning : Proteomics is the global analysis of proteins that covers a broad range of technologies aimed at determining the identity and quantity of proteins expressed in the cell, their three-dimensional structure and interaction partners. In contrast to genome, proteome reflects more accurately on the dynamic state of the cell, tissue, or an organism. LÄS MER

  3. 3. Strategies for Miniaturized Biomarker Detection

    Detta är en avhandling från Department of Biomedical Engineering, Lund university

    Författare :Belinda Adler; Lunds universitet.; Lund University.; [2014]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biomarker; miniturization; lab-on-a-chip; proteomics; PSA; microarray; mass spectrometry; MALDI MS; SPE; sample preparation; immunoaffinity; antibody; aptamer; mass tag; ISET.;

    Sammanfattning : Popular Abstract in Swedish Prostatacancer är en av de vanligaste förekommande cancerformerna. Många äldre män har cancerceller i sin prostata, men som tur är behöver inte all cancer behandlas eftersom den inte växer. I USA får ungefär 27% av alla män prostatacancer och cirka 10% dör av det. LÄS MER

  4. 4. Evaluation of Biomarker Responses in Fish with Special Emphasis on Gill EROD Activity

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Carin Andersson; Uppsala universitet.; [2007]
    Nyckelord :Biology; three-spined stickleback; biomarker; EROD; ethynylestradiol; gill; vitellogenin; spiggin; CYP1A inducers; humic substances; sperm quality; biomonitoring; Biologi;

    Sammanfattning : Many chemicals present in the aquatic environment can interfere with physiological functions in fish. Exposure to chemicals can be revealed by the use of biomarkers. Induction of 7-ethoxyresorufin O-deethylase (EROD) activity is a commonly used biomarker for exposure to CYP1A inducers such as dioxins and polyaromatic hyrdrocarbons. LÄS MER

  5. 5. Biomarker Discovery in Cutaneous Malignant Melanoma A Study Based on Tissue Microarrays and Immunohistochemistry

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Margrét Agnarsdóttir; Uppsala universitet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibody-based proteomics; automated analysis; biomarker; immunohistochemistry; malignant melanoma; survival; tissue microarray; MEDICINE Morphology; cell biology; pathology Morphology Tumour biology; MEDICIN Morfologi; cellbiologi; patologi Morfologi Tumörbiologi; MEDICINE Morphology; cell biology; pathology Pathology; MEDICIN Morfologi; cellbiologi; patologi Patologi; MEDICINE Morphology; cell biology; pathology Pathology Molecular medicine; MEDICIN Morfologi; cellbiologi; patologi Patologi Molekylär medicin; Medical Science; Medicinsk vetenskap; Pathology; Patologi;

    Sammanfattning : The incidence of cutaneous malignant melanoma has increased dramatically in Caucasians the last few decades, an increase that is partly explained by altered sun exposure habits. For the individual patient, with a localized disease, the tumor thickness of the excised lesion is the most important prognostic factor. LÄS MER