Visar resultat 1 - 5 av 52 avhandlingar innehållade ordet muskelsystem.
Sammanfattning : Rheumatoid arthritis (RA) is a chronic autoimmune disease with a largely unknown aetiology. The risk of developing RA is partly dependent on genetic factors, which has motivated extensive efforts to identify the disease regulating genes as away to understand disease pathogenesis. LÄS MER
Sammanfattning : Clubfoot is a congenital disorder, affecting about one of 1000 children. Treatment consists of initial correction of the deformity, followed by prolonged orthosis treatment to maintain the correction obtained. There are several different treatment options. Outcome studies, using reliable and valid instruments are rare. LÄS MER
3. On the etiology and pathogenesis of systemic lupus erythematosus with special reference to environmental factors
Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which environmental factors interact with genetic factors in the development of the disease process and evolution of clinical manifestations. In this thesis both exogenous factors and host factors were investigated, as well as important immunopathological aspects including involvement of immune complex (IC), the complement system and interferon-alpha (IFN-α). LÄS MER
Sammanfattning : This thesis describes the structure and interactions of a novel extracellular matrix protein - PRELP (proline arginine-rich end leucine-rich repeat protein). The amino acid sequence of PRELP showed that it belonged to the leucine-rich repeat (LRR) protein family in connective tissues. LÄS MER
Sammanfattning : The aim was to study prevalence, assessment methods, and risk factors of chronic musculoskeletal pain, as well as effects on health status in a general population setting. A postal survey to a representative sample of 3928 subjects aged 20–74 years in 2 municipalities on the west coast of Sweden was followed by clinical examinations of selected subjects, and a three-year follow up survey to 2425 subjects who answered completely to the first. LÄS MER