Sökning: "Hypertrophy"

Visar resultat 1 - 5 av 136 avhandlingar innehållade ordet Hypertrophy.

  1. 1. Cardiac hypertrophy transcription patterns, hypertrophicprogression and extracellular signalling

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Nina Gennebäck; Umeå universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac hypertrophy; HCM; gene expression; OPLS-DA; multivariate dataanalysis; cardiomyocytes; exosomes; microvesicles; medicin; Medicine;

    Sammanfattning : Background: The aim of this thesis was to study transcription patterns and extracellular signalling of the hypertrophic heart to better understand the mechanisms initiating, controlling and maintaining cardiac hypertrophy.Cardiac hypertrophy is a risk factor for cardiovascular morbidity and mortality. LÄS MER

  2. 2. Metabolic function in adipocytes - focusing on hypertrophy and caveolae

    Detta är en avhandling från Lund University: Faculty of Medicine

    Författare :Björn Hansson; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocyte; hypertrophy; caveolae; adipose tissue; insulin resistance; EHD2; cytoskeleton; cavin 2;

    Sammanfattning : .... LÄS MER

  3. 3. Factors Contributing to Detrusor Overactivity - Obstruction, Hypertrophy and Afferent Nerve Stimulation

    Detta är en avhandling från Annette Schröder, Department of Clinical & Experimental Pharmacology, Lund University Hospital, 221 85 Lund, Sweden

    Författare :Annette Schröder; Lund University.; Lunds universitet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacological sciences; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; knockout; mice; estrogen receptor; EP1 receptor; prostaglandin; rat; endothelin; detrusor overactivity; rabbit; smooth muscle; bladder outlet obstruction; hypertrophy; pharmacognosy;

    Sammanfattning : The consequences of bladder outlet obstruction (BOO) with respect to detrusor hypertrophy, structural and functional changes, and obstruction-induced detrusor overactivity were investigated in vivo and in vitro utilizing various animal models. Possible pathophysiological pathways and therapeutic approaches were tested by drug treatment and the use of knockout models. LÄS MER

  4. 4. Signaling factors related to atrophy and hypertrophy in denervated skeletal muscle

    Detta är en avhandling från Växjö : Linnaeus University Press

    Författare :Ann-Kristin Fjällström; Linnéuniversitetet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Atrophy; Hypertrophy; Skeletal muscle; Denervation; Protein synthesis; Protein degradation; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : The human body consists of about 40 % skeletal muscles which control the body’s movement, ability to stand up, force generation, locomotion, heat production and are also the body’s protein reservoir. Muscle mass is controlled by the relationship between protein synthesis and protein degradation. LÄS MER

  5. 5. Function of contractile and cytoskeletal proteins in smooth muscle: Effects of hypertrophy and age and desmin removal in a transgenic animal

    Detta är en avhandling från Rolf Sjuve, Sölvegatan 19, S-223 62 Lund

    Författare :Rolf Sjuve; Lund University.; Lunds universitet.; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transgenic mouse; desmin; embryonic myosin; isoforms; myosin heavy chain; age; smooth muscle; hypertrophy; Physiology; Fysiologi;

    Sammanfattning : In man, the urinary bladder responds to an urinary outflow obstruction with a pronounced dilatation and growth of the bladder wall. This clinical situation can be mimicked in rat by creation of a partial urinary outflow obstruction and the papers included in the present thesis use this animal model to address questions regarding the adaptive changes in the smooth muscle of the growing bladder. LÄS MER