Sökning: "mice"

Visar resultat 1 - 5 av 2577 avhandlingar innehållade ordet mice.

1. 1. Neurodevelopmental Consequences of Exposure to Paracetamol (Acetaminophen) and Related Drugs : Experimental studies in mice

   Författare :Gaëtan Philippot; Robert Fredriksson; Vesna Jevtovic-Todorovic; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; paracetamol acetaminophen ; developmental neurotoxicology; delta9-tetrahydrocannabinol THC ; ibuprofen; endocannabinoid system; neonatal mice; brain growth spurt; behavior; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

   Sammanfattning : Paracetamol (acetaminophen) is the analgesic pharmaceutical most commonly used during pregnancy and early life. While therapeutic doses of paracetamol are considered harmless during these periods, recent findings in both humans and rodents suggest a link between developmental exposure to paracetamol and behavioral consequences later in life. LÄS MER

3. 2. Vascular Wall Responses to Bypass Grafting - Studies in Mice

   Författare :Klas Österberg; Göteborgs universitet; []
   Nyckelord :Intimal hyperplasia; graft stenosis; smooth muscle cells; mice; cellular recruitment;

   Sammanfattning : Abstract Vein grafts are frequently used in bypass surgery for treatment of coronary artery disease and lower limb ischemia. Unfortunately the long-term patency is impaired by vein graft stenoses due to intimal hyperplasia (IH). It is assumed that exaggerated intimal thickening is initiated by vessel wall injuries or local flow disturbances. LÄS MER

4. 3. THE ANGIOGENIC RESPONSE IN HYPOXIC HEART. Experimental studies in mice

   Författare :Fei Tian; Göteborgs universitet; []
   Nyckelord :hypoxia; angiogenesis; mice; endoglin; SUMO; PDI;

   Sammanfattning : Coronary artery disease is the leading cause of death in the western world today. Although induction of angiogenesis would appear to be an ideal therapeutic strategy, clinical trials of proangiogenic factors have proved disappointing. LÄS MER

5. 4. The expression and function of CD25 B cells in man and in mice

   Författare :Amu Sylvie; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cell; CD25; rheumatoid arthritis; systemic lupus erythematosus; mice;

   Sammanfattning : B cells play an important role both in the physiology and pathology of immune responses by production of antibodies, cytokines and by presentation of antigens. It has been shown that human CD25 expressing B cells display a mature phenotype, perform better as antigen presenting cells but secrete less immunoglobulins. LÄS MER

7. 5. T-cell Differentiation and Immunological Homeostasis in Lymphopenic and Kappa Light Chain Deficient Mice

   Författare :Frida Ekholm Pettersson; Fredrik Ivars; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; T cells; differentiation; homeostasis; cytokines; mice; SCID; κ-deficient; Biokemi; Biochemistry; Biokemi; immunologi; Immunology;

   Sammanfattning : T lymphocytes are primarily involved in adaptive, cell-mediated, immune reactions. In this thesis T cells were studied regarding central and peripheral differentiation and homeostatic mechanisms for maintanance of the immune repertoire.The influence by mature T cells on thymic development was studied in C. LÄS MER