Sökning: "Farmakologi"
Visar resultat 1 - 5 av 854 avhandlingar innehållade ordet Farmakologi.
1. Development and Evaluation of Nonparametric Mixed Effects Models
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : A nonparametric population approach is now accessible to a more comprehensive network of modelers given its recent implementation into the popular NONMEM application, previously limited in scope by standard parametric approaches for the analysis of pharmacokinetic and pharmacodynamic data.The aim of this thesis was to assess the relative merits and downsides of nonparametric models in a nonlinear mixed effects framework in comparison with a set of parametric models developed in NONMEM based on real datasets and when applied to simple experimental settings, and to develop new diagnostic tools adapted to nonparametric models. LÄS MER
2. Spontaneous reporting of adverse drug reactions Possibilities and limitations
Detta är en avhandling från Umeå : Farmakologi och klinisk neurovetenskapSammanfattning : Adverse drug reactions (ADRs) constitute a major problem in society and in drug therapy. They are a common cause of short-term hospitalization, prolonged hospitalization and death. Spontaneous reporting of ADRs remains one the most effective methods for detecting new and serious drug reactions. LÄS MER
3. Fatty acid amide hydrolase - A target for anti-inflammatory therapies?
Detta är en avhandling från Umeå : Farmakologi och klinisk neurovetenskapSammanfattning : Anti-inflammatory drugs are a widely used class of therapeutic agents, but the use of non-steroidal anti-inflammatory drugs (NSAID) is hampered by their gastrointestinal side-effects. Recent reports that cyclooxygenase-2 inhibitors may cause cardiovascular events underline the importance of identifying new therapeutic strategies for the treatment of inflammation. LÄS MER
4. Pharmacology of Palmitoylethanolamide and Related Compounds
Detta är en avhandling från Umeå : Farmakologi och klinisk neurovetenskapSammanfattning : Anandamide (AEA) is an endogenous fatty acid which activates the same cannabinoid receptors as ∆9-tetrahydrocannabinol, the psychoactive substance in marijuana. In vivo, anandamide exerts a number of actions including effects upon pain and inflammation. LÄS MER
5. Transcription Factor AP-2 in Relation to Serotonergic Functions in the Central Nervous System
Detta är en avhandling från Uppsala : Acta Universitatis UpsaliensisSammanfattning : Eukaryotic gene transcription plays a regulatory role in mammalian developmental processes. It has been shown that transcriptional control is an important mechanism for specification of neurotransmitter phenotypes. LÄS MER
