Sökning: "Cardiac hypertrophy"

Visar resultat 1 - 5 av 51 avhandlingar innehållade orden Cardiac hypertrophy.

  1. 1. Cardiac hypertrophy : transcription patterns, hypertrophic progression and extracellular signalling

    Författare :Nina Gennebäck; Stellan Mörner; Anders Waldenström; Urban Hellman; Ali J Marian; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac hypertrophy; HCM; gene expression; OPLS-DA; multivariate dataanalysis; cardiomyocytes; exosomes; microvesicles; Medicine; medicin;

    Sammanfattning : Background: The aim of this thesis was to study transcription patterns and extracellular signalling of the hypertrophic heart to better understand the mechanisms initiating, controlling and maintaining cardiac hypertrophy.Cardiac hypertrophy is a risk factor for cardiovascular morbidity and mortality. LÄS MER

  3. 2. Lung Emphysema & Cardiac Function

    Författare :Kirsten Jörgensen; Göteborgs universitet; []
    Nyckelord :emphysema; hemodynamics; ventricular end-diastolic volumes; lung volume reduction; ventricular function; transoesophageal echocardiography; magnetic resonance imaging; diastole; simendan; hypertrophy;

    Sammanfattning : Patients with severe lung emphysema have poor quality of life because of impaired lung function and reduced exercise tolerance. Concomitant heart disease in severe emphysema is well recognised. The prevailing view is that mainly the right side of the heart is involved, while the issue of left ventricular (LV) involvement is less studied. LÄS MER

  4. 3. Metabolic aspects of cardiac arrhythmias

    Författare :Sigfus Gizurarson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiologi; Electrofysiologi; Djurexperiment; Metabolism;

    Sammanfattning : Cardiac arrhythmias are an important cause of mortality and morbidity in patients with cardiac diseases. Sudden death due to ventricular tachycardia and fibrillation (VT/VF) in the setting of acute myocardial infarction (AMI) and heart failure (HF) is a frequent cause of premature death. LÄS MER

  5. 4. The role of fibroblast growth factor-23 in chronic kidney disease-mineral and bone disorder

    Författare :Majd A. I. Mirza; Tobias Larsson; Tilman Drüeke; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FGF23; FGF-23; CKD; CKD-MBD; cardiovascular disease; vascular function; atherosclerosis; hypertrophy; LVMI; LVH; fractures; bone; fat mass; obesity; apolipoproteins; cholesterol; lipids; Kidney diseases; Njursjukdomar; Cardiovascular medicine; Kardiovaskulär medicin; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Fibroblast growth factor-23 (FGF23) was initially identified as the causative factor of autosomal dominant hypophosphatemic rickets. Further studies confirmed that FGF23 is predominantly expressed in the osteocytes and osteoblasts of bone and that circulating FGF23 acts on the kidney to inhibit renal phosphate reabsorption and 1,25(OH)2D3 hydroxylation. LÄS MER

  7. 5. Studies on malignant ventricular tachyarrhythmias and their treatment with an implantable defibrillator

    Författare :Bengt Sandstedt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Implantable cardioverter defibrillator; ventricular fibrillation; ventricular tachycardia; predischarge test; defibrillation threshold; discrimination; electrogram morphology; aortic stenosis; hypertrophy; noradrenalin;

    Sammanfattning : Aims: To investigate the hemodynamic, metabolic and autonomic effects of ventricular fibrillation per se during maintained circulation. To study the defibrillation threshold (DFT) and efficacy of a new and thinner ICD lead (DSP) compared with the standard lead (C). LÄS MER