Sökning: "estrogen receptor"

Visar resultat 1 - 5 av 237 avhandlingar innehållade orden estrogen receptor.

  1. 1. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking

    Detta är en avhandling från Experimentel medicinsk vetenskap, Lunds Universitet

    Författare :Caroline Sandén; Lund University.; Lunds universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; receptor trafficking; B1 receptor; receptor oligomerization; estrogen; GPER1; G protein-coupled estrogen receptor 1; EP24.15; BK; bradykinin; B1R; B2R; B2 receptor; GPCR; receptor maturation;

    Sammanfattning : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. LÄS MER

  2. 2. Immunomodulation by estrogen and estren

    Detta är en avhandling från Experimentel medicinsk vetenskap, Lunds Universitet

    Författare :Ulrika Islander; Göteborgs universitet.; Gothenburg University.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; estrogen receptor knock-out mice; estrogen; estren; estrogen receptor; lymphopoiesis; T cells; B cells; immunoglobulin; inflammation;

    Sammanfattning : Estrogen affects the development and regulation of the immune system. Treatment of gonadectomized mice with estrogen results in suppression of T and B lymphopoiesis, as well as decreased delayed type hypersensitivity reaction, granulocyte mediated inflammation and levels of IL-6 in serum. LÄS MER

  3. 3. Expression and function of vascular estrogen receptors alpha and beta

    Detta är en avhandling från Min Liang, BMC F12, 221 84 Lund, Sweden

    Författare :Min Liang; Lund University.; Lunds universitet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetologi; diabetology; Endokrinologi; sekretion; ubiquitin-proteasome pathway; MIP-2; MCP-1; iNOS; estrogen receptor knockout; estrogen receptor; aorta; estrogen;

    Sammanfattning : Estrogen receptors (ER) are expressed not only in classical target organs for estrogen like breast and uterus, but also in male reproductive system as well as in non-reproductive organs such as brain, liver and bone. The functions of ER are quite well known in reproductive organs but less information is available regarding their function in vascular tissue. LÄS MER

  4. 4. Estrogen and Glucocorticoid Metabolism

    Detta är en avhandling från Umeå : Institutionen för Folkhälsa och Klinisk Medicin

    Författare :Therése Andersson; Umeå universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11β-Hydroxysteroid Dehydrogenase Type 1; Estrogen; Cortisol; Adipose tissue; Liver; Menopause; Ovariectomy; Adipocyte; Estrogen Receptor β; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Endocrinology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Endokrinologi; medicin; Medicine;

    Sammanfattning : Background: Cardiovascular disease (CVD) is the leading cause of death among women in Sweden. The risk of CVD increases rapidly after the menopause. A major contributing factor may be the redistribution of adipose tissue, from the peripheral to central depots, associated with menopause. LÄS MER

  5. 5. Erythropoietin receptor in growth control and anti-estrogen resistance of estrogen receptor positive breast cancer

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Susann Reinbothe; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tamoxifen resistance; proliferation; PI3k pathway; Breast cancer; erythropoietin receptor; estrogen receptor;

    Sammanfattning : The main function of Erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis. Therefore, recombinant human EPO (rhEPO) is used to treat anemia in cancer patients, but some studies have reported that rhEPO treatment might promote tumor progression. Additionally, EPOR expression has been detected in various cancer forms. LÄS MER