Sökning: "detrusor overactivity"

Hittade 4 avhandlingar innehållade orden detrusor overactivity.

  1. 1. Factors Contributing to Detrusor Overactivity - Obstruction, Hypertrophy and Afferent Nerve Stimulation

    Författare :Annette Schröder; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacological sciences; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; knockout; mice; estrogen receptor; EP1 receptor; prostaglandin; rat; endothelin; detrusor overactivity; rabbit; smooth muscle; bladder outlet obstruction; hypertrophy; pharmacognosy;

    Sammanfattning : The consequences of bladder outlet obstruction (BOO) with respect to detrusor hypertrophy, structural and functional changes, and obstruction-induced detrusor overactivity were investigated in vivo and in vitro utilizing various animal models. Possible pathophysiological pathways and therapeutic approaches were tested by drug treatment and the use of knockout models. LÄS MER

  2. 2. Central nervous system targets for micturition control

    Författare :Rikard Pehrson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; central nervous system; Micturition; 5-HT; GABA; tramadol; NAD-299; CGP62349; apomorphine; cerebral infarction; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences;

    Sammanfattning : Normal urine storage and bladder emptying are controlled by the central (CNS) as well as the peripheral nervous system. Dysfunction of these mechanisms can lead to urinary incontinence. Urinary tract dysfunctions have symptomatically been treated mainly with drugs acting peripherally. LÄS MER

  3. 3. On the natural history, diagnosis and treatment of benign prostatic hyperplasia

    Författare :Stepan Vesely; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Lower urinary tract symptoms LUTS ; benign prostatic hyperplasia BPH ; bladder outlet obstruction; transurethral prostatectomy TURP ; transurethral microwave thermotherapy TUMT ;

    Sammanfattning : There are a number of important issues which remain unknown or poorly understood in the natural history of benign prostatic hyperplasia (BPH). The standard investigation of patients with BPH gives controversial results in relation to the severity of lower urinary tract symptoms (LUTS). LÄS MER

  4. 4. Longitudinal study of infants with high-grade vesicoureteral reflux

    Författare :Sofia Sjöström; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; SAMHÄLLSVETENSKAP; MEDICAL AND HEALTH SCIENCES; SOCIAL SCIENCES; vesico-ureteral reflux; congenital; infant; kidney function tests; renal insufficiency; urinary tract infections; bladder; urodynamics; spontaneous resolution; multivariate analyses;

    Sammanfattning : Background: Infants with congenital high-grade vesicoureteral reflux (VUR) have been regarded as a special group amongst children with reflux, with their own characteristics concerning renal damage, gender, resolution rate and causative mechanism. A dysfunctional bladder has been suggested to be associated with the condition. LÄS MER