Sökning: "EHD2"

Hittade 4 avhandlingar innehållade ordet EHD2.

  1. 1. Caveolae associated proteins and how they effect caveolae dynamics

    Författare :Björn Morén; Richard Lundmark; Volker Haucke; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Caveolae; caveolin; EHD2; cavin; microdomain; microscopy; TIRF; AFM; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Caveolae are a type of invaginated membrane domain that has been shown to be involved in several disease states, including lipodystrophy, muscular dystrophies and cancer. Several of these diseases are caused by the lack of caveolae or caveolae-related signaling deficiencies in the tissues in which the caveolar domain are abundant such as lung, adipose, muscle and their related endothelial cells. LÄS MER

  3. 2. Metabolic function in adipocytes - focusing on hypertrophy and caveolae

    Författare :Björn Hansson; Glukostransport och proteintrafficking; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocyte; hypertrophy; caveolae; adipose tissue; insulin resistance; EHD2; cytoskeleton; cavin 2;

    Sammanfattning : .... LÄS MER

  4. 3. Regulation of assembly and cell surface dynamics of caveolae

    Författare :Jagan Mohan; Richard Lundmark; Oleg Shupliakov; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : A typical mammalian cell plasma membrane displays a high level of plasticity counter balanced with stability. The plasma membrane show various kinds of invaginations to meet physiological demands of the cells such as nutrient uptake, receptor signaling etc. An example of one such invagination observed in many cell types is “Caveola”. LÄS MER

  5. 4. Adipocyte size and function in the epididymal and inguinal fat depots

    Författare :Claes Fryklund; Glukostransport och proteintrafficking; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Adipocytes; Inguinal fat; Epididymal fat; Insulin resistance; Hypertrophy; Hyperplasia;

    Sammanfattning : Nearly 60% of the worlds adult population is projected to be overweight or obese by 2030. The prevalence of obesity- related diseases, such as type 2 diabetes (T2D), has increased markedly in the past decades. The adipose tissue plays an important role in disease progression of T2D. LÄS MER