Sökning: "pharmacognosy"

Visar resultat 1 - 5 av 79 avhandlingar innehållade ordet pharmacognosy.

  1. 1. Cytotoxic Compounds of Plant Origin – Biological and Chemical Diversity

    Författare :Petra Lindholm; Anders Backlund; Lars Bohlin; Kristín Ingólfsdóttir; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacognosy; pharmacognosy; cytotoxicity; antitumour; Nuphar alkaloid; cyclotide; thionin; cardiac glycoside; Farmakognosi; Pharmacognosy; Farmakognosi;

    Sammanfattning : The development of resistance by tumour cells to chemotherapeutic agents is a major problem in cancer treatments. One way to counter this is to find compounds with cytotoxic mechanisms other than those of drugs in clinical use today. LÄS MER

  3. 2. Exploring evolutionary and chemical space using chemoinformatic tools and traditional methods in pharmacognosy

    Författare :Astrid Henz Ryen; Anders Backlund; Thierry Kogej; Fernando B. Da Costa; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; angiosperm chemistry; physicochemical properties of plant specialized metabolites; chemical diversity; chemical space; sesquiterpene lactones; scaffold diversity; molecular framework; cluster analysis; ECFP6; Lindera benzoin; sesquiterpenes; anti-inflammatory; Farmakognosi; Pharmacognosy;

    Sammanfattning : The number of new drugs coming to the market is declining while interest in lead discovery from natural resources is seeing a revival. Although methods for isolation and identification of natural products have advanced tremendously, methods for selection of potential leads have fallen behind. LÄS MER

  4. 3. Polyporoid fungi of Tanzania : Taxonomy, transcriptomics and biochemical analyses of Kusaghiporia usambarensis and Piptoporellus baudonii

    Författare :Juma Mahmud Hussein; Sanja Tibell Savić; Donatha Tibuhwa; Christina Wedén; Ulf Göransson; Jan Stenlid; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Systematics; Laetiporaceae; pharmacognosy; cysteine-rich peptide; baudonii; Biology with specialization in Systematics; Biologi med inriktning mot systematik;

    Sammanfattning : Polyporoid fungi refers to basidiomycetes with fruiting bodies with the hymenium located to the inner surfaces of pores or narrow tubes. The majority of polyporoids belongs to Polyporales. Most Polyporales are saprobes, but some are plant pathogens. LÄS MER

  5. 4. Vasodilator actions of EDHF and anandamide

    Författare :David Andersson; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vanilloid receptors; afferent neurons; anandamide; cannabinoids; potassium channels; hyperpolarization; vasodilation; Vascular endothelium; arteries; airways; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : Vasodilator responses to endothelium-derived hyperpolarizing factor (EDHF) and anandamide in isolated arteries were investigated. A combination of the potassium channel blockers charybdotoxin and apamin inhibits EDHF-mediated relaxations. LÄS MER

  7. 5. Biological significance of ECL-cell histamine

    Författare :Kjell Andersson; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; ultrastructure; gastric acid secretion; a-fluoromethylhistidine a-FMH ; stomach; oxyntic mucosa; histidine decarboxylase HDC ; Enterochromaffin-like ECL cell; histamine; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Sammanfattning : In the oxyntic mucosa of the mammalian stomach, histamine is stored in enterochromaffin-like (ECL) cells and in mucosal mast cells. The activity of the histamine-forming enzyme, histidine decarboxylase (HDC), is high in ECL cells but lower in the mucosal mast cells. LÄS MER