Sökning: "gene expression"

Visar resultat 1 - 5 av 3192 avhandlingar innehållade orden gene expression.

  1. 1. Contributions to Statistical Analysis of Gene Expression Data

    Detta är en avhandling från Göteborg : Chalmers University of Technology

    Författare :Anders Sjögren; Göteborgs universitet.; Gothenburg University.; [2005]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA microarray; differential expression; gene regulation; variance stabilising transformation; permutation; reference gene; housekeeping gene; bootstrap; quality control QC ; quality assurance QA ; quality assessment; empirical Bayes; weighted moderated t-statistic; WAME; quality assessment; gene regulation; housekeeping gene; permutation; reference gene; variance stabilising transformation; empirical Bayes; quality control QC ; differential expression; bootstrap; weighted moderated t-statistic; quality assurance QA ; WAME;

    Sammanfattning : .... LÄS MER

  2. 2. Statistical analysis of gene expression data

    Detta är en avhandling från Göteborg : Chalmers University of Technology

    Författare :Erik Kristiansson; Göteborgs universitet.; Gothenburg University.; [2007]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gene expression; DNA microarrays; linear models; empirical Bayes; quality control; gene regulation; categorical data analysis; logistic regression; heavy metal stress; ecotoxicology; linear models; categorical data analysis; heavy metal stress; logistic regression; DNA microarrays; empirical Bayes; ecotoxicology; quality control; gene regulation;

    Sammanfattning : Microarray technology has become one of the most important tools for genome-wide mRNAmeasurements. The technique has been successfully applied to many areas in modernbiology including cancer research, identification of drug targets, and categorization of genesinvolved in the cell cycle. LÄS MER

  3. 3. Gene Expression Studies of Hematologic Malignacies

    Detta är en avhandling från Divison of Clinical Genetics

    Författare :Anna Andersson; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; cancer; onkologi; Cytologi; oncology; Cytology; acute myeloid leukemia; acute lymphoblastic leukemia; normal hematopoietic cells; cDNA microarray; gene expression profiling; hematopoiesis; pediatric leukemia; fusion gene; Pediatrics; Pediatri; Clinical genetics; Klinisk genetik; cancerology; Hematologi; extracellulära vätskor;

    Sammanfattning : The general aim of this thesis was to characterize hematologic malignancies using gene expression profiling in order to obtain an improved classification and to study deregulated transcriptional networks in leukemia. In the first study (Article I), the gene expression profiles of hematologic cell lines were analyzed to investigate whether such cell lines maintain expression profiles that are characteristic of their primary genetic changes. LÄS MER

  4. 4. Avian Genome Evolution - Gene Expression, Gene Divergence and Sexual Dimorphism

    Detta är en avhandling från Divison of Clinical Genetics

    Författare :Sara Naurin; [2009]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sex chromosome; avian genome evolution; gene expression; sexual dimorphism; Z chromosome;

    Sammanfattning : This study has focused on: (i) differences in how males and females use the genes in the genome, (ii) how sex chromosomes evolve and (iii) how the evolutionary rate of genes are affected by the chromosome on which they are located on and the gene expression level they experience. A large-scale microarray was developed for the zebra finch, Taeniopygia guttata and techniques were developed so that this microarray could also be used for wild passerine birds. LÄS MER

  5. 5. Gene expression in carcinogenesis

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Författare :Heléne Fischer; Karolinska Institutet.; Karolinska Institutet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : It is important to understand the processes of carcinogenesis and to find out which genes are involved . One way to study the process on a molecular basis is to identify differences in gene expression. LÄS MER