Sökning: "Annette Schröder"

Hittade 1 avhandling innehållade orden Annette Schröder.

1. 1. Factors Contributing to Detrusor Overactivity - Obstruction, Hypertrophy and Afferent Nerve Stimulation

   Författare :Annette Schröder; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacological sciences; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; knockout; mice; estrogen receptor; EP1 receptor; prostaglandin; rat; endothelin; detrusor overactivity; rabbit; smooth muscle; bladder outlet obstruction; hypertrophy; pharmacognosy;

   Sammanfattning : The consequences of bladder outlet obstruction (BOO) with respect to detrusor hypertrophy, structural and functional changes, and obstruction-induced detrusor overactivity were investigated in vivo and in vitro utilizing various animal models. Possible pathophysiological pathways and therapeutic approaches were tested by drug treatment and the use of knockout models. LÄS MER