Sökning: "virulence regulation"

Visar resultat 11 - 15 av 86 avhandlingar innehållade orden virulence regulation.

  1. 11. Twin-arginine translocation in Yersinia : the substrates and their role in virulence

    Författare :Ummehan Avican; Åke Forsberg; Åsa Sjöling; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Yersinia pseudotuberculosis; Tat; virulence; Tat substrates; SufI; stress response; metabolism; infection; transcriptome analysis; Infectious Diseases; infektionssjukdomar; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Sammanfattning : Pathogenic Yersinia cause a manifold of diseases in humans ranging from mild gastroenteritis (Y. pseudotuberculosis and Y. enterocolitica) to pneumonic and bubonic plague (Y. LÄS MER

  2. 12. Stress response and virulence in Vibrio anguillarum

    Författare :Barbara Weber; Debra L. Milton; James D. Oliver; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Vibrio anguillarum; quorum sensing; Type VI secretion; stress response; virulence; skin colonization; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Bacteria use quorum sensing, a cell to cell signaling mechanism mediated by small molecules that are produced by specific signal molecule synthases, to regulate gene expression in response to population density. In Vibrio anguillarum, the quorum-sensing phosphorelay channels information from three hybrid sensor kinases VanN, VanQ, CqsS that sense signal molecules produced by the synthases VanM, VanS and CqsA, onto the phosphotransferase VanU, to regulate activity of the response regulator VanO. LÄS MER

  3. 13. Small Molecules as Tools in Biological Chemistry : Effects of Synthetic and Natural Products on the Type III Secretion System

    Författare :Caroline E. Zetterström; Mikael Elofsson; Samuel I. Miller; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Type III secretion; salicylidene acylhydrazide; virulence-blocker; virulence; inhibitor; target identification; neohopeaphenol A; Yersinia pseudotuberculosis; Pseudomonas aeruginosa; Escherichia coli; biologisk kemi; biological chemistry;

    Sammanfattning : The increasing use of antibiotics has led to a huge problem for society, as some bacteria have developed resistance towards many of the antibiotics currently available. To help find solutions to this problem we studied small molecules that inhibit bacterial virulence, the ability to cause disease. LÄS MER

  4. 14. Escherichia coli Fimbriae, Bacterial Persistence and Host Response Induction in the Human Urinary Tract

    Författare :Göran Bergsten; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; bacteriology; Microbiology; IL-8; IL-6; neutrophils; GFP; mucosal host response; Type 1 fimbriae; P fimbriae; adherence; virulence factors; regulation; deliberate colonisation; Escherichia coli 83972; Urinary tract infection; asymptomatic bacteriuria;

    Sammanfattning : Urinary tract infections (UTI) are among the most common bacterial infections in humans. Symptomatic UTIs may be acute, recurrent or chronic but the most frequent form of UTI is asymptomatic bacteruria (ABU). In ABU, the mucosa remains inert, despite the presence of large bacterial numbers in urine. LÄS MER

  5. 15. Bacterial Regulation of Peripheral Immunity : Mechanistic insights from lactobacilli and Staphylococcus aureus

    Författare :Manuel Mata Forsberg; Eva Sverremark-Ekström; Monika Brunner-Weinzierl; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Immune regulation; Cytokines; T cells; gamma-delta T cells; MAIT cells; NK cells; Lactobacillus; Staphylococcus aureus; staphylococcal enterotoxins; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : There is a constant cross-talk between our immune system and the colonizing microbiota. The gut resident bacteria produce a broad range of molecules with regulatory activities in both local and distal tissues. Staphylococcus (S. LÄS MER