Sökning: "IL-8"

Visar resultat 1 - 5 av 224 avhandlingar innehållade ordet IL-8.

  1. 1. Neutrophil Chemotaxis and Respiratory Burst in Term and Preterm Newborn Infants

    Författare :Maria Stålhammar; Richard Sindelar; Jens Schollin; Uppsala universitet; []
    Nyckelord :innate immunity; neutrophil; term newborn infants; preterm newborn infants; chemotaxis; respiratory burst; reactive oxygen species; cell surface receptor; IL-8; bacterial N-formyl peptide;

    Sammanfattning : Neutrophil activation is the most important initial immune defense against invading microbes in newborn infants. The reduced neutrophil migration and uncontrolled regulation of reactive oxygen species (ROS) production observed in neonates, could result in a diminished infectious response or in tissue damage. LÄS MER

  3. 2. Effects of hypoxia on macrophage function in atherosclerosis

    Författare :Ellen Knutsen Rydberg; Göteborgs universitet; []
    Nyckelord :atherosclerosis; hypoxia; macrophage; IL-8; oxidized LDL; oxysterols; 15-lipoxygenase-2;

    Sammanfattning : Atherosclerosis is a complex disease, which affects large and medium sized arteries and is characterized by an arterial wall thickening. A constant supply of oxygen is needed to maintain cell functions in the atherosclerotic plaque. The oxygen distribution to the cells in the arterial wall depends on diffusion. LÄS MER

  4. 3. Clinical, biochemical and morphological aspects of cervical ripening in the first trimester

    Författare :Nina Vukas Radulovic; Göteborgs universitet; []
    Nyckelord :cervical ripening; misoprostol; nitric oxide; electron microscopy; miscarriage; IL-8; MMP-1; MMP-8; MMP-9;

    Sammanfattning : Background: The uterine cervix has the ability to be transformed from being a rigid organ in non-pregnant women to become a loose structure that dilates and allows passage of the foetus at parturition. This process, cervical ripening, has been described similar to an inflammatory reaction of the extracellular matrix involving activation of inflammatory cytokines, matrix metalloproteinases and breakdown of the collagen framework. LÄS MER

  5. 4. Interleukin-17 in non-allergic airway inflammation

    Författare :Martti Laan; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-17; airway inflammation; bronchial epithelial cells; neutrophils; T-lymphocytes; IL-8; IL-6; MAP kinases.;

    Sammanfattning : Chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchial asthma and cystic fibrosis are common clinical disorders all characterized by airway neutrophilia. By releasing proteolytic enzymes and free oxygen radicals, neutrophils can contribute to the main features of these diseases such as airway obstruction, hypersecretion and remodelling. LÄS MER

  7. 5. Mast cells in Hodgkin lymphoma : or 'What's a nice cell like you doing in a tumour like this?'

    Författare :Marie Fischer; Gunnar Nilsson; Gunilla Enblad; Tor Olofsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Hodgkin lymphoma; mast cells; CD30; CD30L; IL-9; CCL5; atopic dermatitis; psoriasis; IL-8; Patologi; Pathology; Patologi;

    Sammanfattning : Mast cell (MC) accumulation around tumours is an old observation gaining new relevance due to the multifaceted nature of MCs and their many roles in immunity, beyond allergy. Knowledge about tumour specific recruitment of, and interactions with, MCs is needed to unravel the function of their presence. LÄS MER