Sökning: "biologisk kemi"

Visar resultat 1 - 5 av 48 avhandlingar innehållade orden biologisk kemi.

  1. 1. Biolubricants and Biolubrication

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Min Wang; KTH.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Hyaluronan; Phospholipid; Lubricin; Cartilage Oligomeric Matrix Protein; COMP; Adsorption; Surface Force; Friction; Biolubrication; Boundary Lubrication; Load Bearing Capacity; Synergistic Effects; DLS; QCM-D; AFM.; Hyaluronan; Fosfolipid; Lubricin; Cartilage Oligomeric Matrix Protein; COMP; Adsorption; Ytkraft; Friktion; Biologisk smörjning; Gränsskiktssmörjning; Lastbärande förmåga; Synergieffekter; DLS; QCM-D; AFM.; Kemi; Chemistry;

    Sammanfattning : The main objective of this thesis work was to gain understanding of the principles of biolubrication, focusing on synergistic effects between biolubricants. To this end surface force and friction measurements were carried out by means of Atomic Force Microscopy, using hydrophilic and hydrophobic model surfaces in salt solutions of high ionic strength (≈ 150 mM) in presence of different biolubricants. LÄS MER

  2. 2. Aspects of Porous Graphitic Carbon as Packing Material in Capillary Liquid Chromatography

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anna Törnkvist; Uppsala universitet.; [2003]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; PGC; porous graphitic carbon; stationary phase; packing material; LC; liquid chromatography; miniaturized; chiral; enantiomer; ESI; electrospray ionization; mass spectrometry; polar compounds; L-DOPA; dopamine; biological samples; biological matrix; Analytisk kemi; PGC; poröst grafitiserat kol; stationärfas; packningsmaterial; LC; vätskekromatografi; miniatyriserade system; kiral; enantiomer; ESI; electrospray jonisation; mass spektrometri; polära föreningar; L-DOPA; dopmamine; biologiska prover; biologisk matris; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; Analytical Chemistry; Analytisk kemi;

    Sammanfattning : In this thesis, porous graphitic carbon (PGC) has been used as packing material in packed capillary liquid chromatography. The unique chromatographic properties of PGC has been studied in some detail and applied to different analytical challenges using both electrospray ionization-mass spectrometry (ESI-MS) and ultra violet (UV) absorbance detection. LÄS MER

  3. 3. Synthesis of Spiro-bicyclo[2.2.2]Octane Derivatives Towards the Development of Paclitaxel Mimetics

    Detta är en avhandling från Organic Chemistry, Lund University

    Författare :Viveca Thornqvist; Lund University.; Lunds universitet.; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi; Organic chemistry; Organisk kemi; Chemistry; Natural science; paclitaxel; spiro; indium; Naturvetenskap; bicyclo[2.2.2]octane; allylation; paclitaxel mimetic;

    Sammanfattning : Many of the drugs that are developed in the pharmaceutical industry have their origin in natural products. Paclitaxel, the active substance of the medicine Taxol, was found in the bark of the Pacific yew tree (Taxus brevifolia). LÄS MER

  4. 4. Protein Interactions: Electrostatics and Ligand Binding

    Detta är en avhandling från Department of Biophysical Chemistry, Lund University

    Författare :Ingemar André; Lund University.; Lunds universitet.; [2005]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; Molekylär biofysik; secondary structure formation; protein GB1; pKa values; pH stability; NMR; electrostatic interactions; M proteins; calbindin D9k; calcium binding; cooperativity; calmodulin; calbindin D28k;

    Sammanfattning : This thesis deals with Ca2+ binding to proteins, electrostatic interactions in and between proteins as well as inter- and intramolecular interactions. A computer program was developed to determine Ca2+ binding constants from experimental titration data of proteins. LÄS MER

  5. 5. Water-swelling tablets based on hydrophobically modified poly(acrylic acid) - Effects of amphiphiles on swelling and drug release

    Detta är en avhandling från Department of Chemistry, Lund University

    Författare :Patrik Knöös; Lund University.; Lunds universitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drug deliver; Controlled release; Hydrophobically modified polymers; Surfactant-polymer interactions; Poorly soluble drug;

    Sammanfattning : An important issue within the pharmaceutical world today is the increasing number of poorly soluble drugs. These often show a low bioavailability and a susceptibility to varying conditions in the intestine. LÄS MER