Sökning: "mucosal host response"

Visar resultat 1 - 5 av 58 avhandlingar innehållade orden mucosal host response.

  1. 1. Escherichia coli Fimbriae, Bacterial Persistence and Host Response Induction in the Human Urinary Tract

    Författare :Göran Bergsten; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; bacteriology; Microbiology; IL-8; IL-6; neutrophils; GFP; mucosal host response; Type 1 fimbriae; P fimbriae; adherence; virulence factors; regulation; deliberate colonisation; Escherichia coli 83972; Urinary tract infection; asymptomatic bacteriuria;

    Sammanfattning : Urinary tract infections (UTI) are among the most common bacterial infections in humans. Symptomatic UTIs may be acute, recurrent or chronic but the most frequent form of UTI is asymptomatic bacteruria (ABU). In ABU, the mucosa remains inert, despite the presence of large bacterial numbers in urine. LÄS MER

  3. 2. Mechanisms of microbial-host interaction during asymptomatic bacteriuria

    Författare :Jenny Grönberg Hernandez; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asymptomatic bacteriuria; Urinary tract infection; Escherichia coli 83972; IRF3; TLR4; Evolution; host response; promoter polymorphisms; transcription; P fimbriae; Type 1 fimbriae;

    Sammanfattning : Urinary tract infections (UTIs) present an interesting and relevant model for studying microbial adaptation. After establishing significant numbers, the bacteria either cause severe disease, or an asymptomatic carrier state resembling the normal flora at other mucosal sites. LÄS MER

  4. 3. The interplay between Giardia intestinalis and host intestinal epithelial cells : A tale of immune activation and suppression

    Författare :Jana Grüttner; Staffan Svärd; Mikael E. Sellin; Steven Singer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Giardia; diarrhea; RNAseq; proteomics; small intestinal epithelial cells; enteroids; organoids; protozoan; differentiation; immune response; host-parasite interaction; swimming; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : Giardia intestinalis is a non-invasive, protozoan parasite causing the diarrheal disease giardiasis in a variety of mammals, including humans. The parasite has two main life cycle stages; disease-causing trophozoites and infectious cysts. Trophozoites colonize the host’s upper small intestine by attaching to intestinal epithelial cells (IECs). G. LÄS MER

  5. 4. Mucosal immunity in the respiratory tract : The role of IgA in protection against intracellular pathogens

    Författare :Ariane Rodríguez; Carmen Fernández; Lennart Hammarström; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosal immunity; respiratory tract; IgA; intracellular pathogens; Immunology; Immunologi;

    Sammanfattning : The lungs and upper airways are mucosal surfaces that are common site for infection with an enormous variety of inhaled pathogens. Therefore, induction of immune responses in the respiratory tract is crucial for protection against respiratory diseases. One of the pathogens infecting the host via the respiratory tract is Mycobacterium Tuberculosis. LÄS MER

  7. 5. The role of P fimbriae for Escherichia coli establishment and mucosal inflammation in the human urinary tract

    Författare :Björn Wullt; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; asymptomatic bacteriuria; urinary tract infections; deliberate colonization; E. coli 83972; P-fimbriae; Mucosal host response; IL-6; IL-8; neutrophils; regulation.; GFP; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Bacterial adhesion to the bladder mucosa is a critical step for the establishment of Escherichia coli bacteriuria. The P-fimbriae, encoded by the pap gene cluster, are considered as virulence factors but the mechanisms have been debated. This study defined the roles for P fimbriation during the early colonization of the human urinary tract. LÄS MER