Sökning: "reperfusion injury"

Visar resultat 1 - 5 av 88 avhandlingar innehållade orden reperfusion injury.

  1. 1. Pulmonary Injury Following Intestinal Ischemia and Reperfusion in Rats

    Detta är en avhandling från Department of Surgery, Clinical Sciences Lund, Lund University

    Författare :Anna Börjesson; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reperfusion injury; intestinal ischemia; pulmonary injury; endothelium; cytokines; alveolar fluid clearance; leukocytes; orthopaedics; Surgery; traumatology; ortopedi; Kirurgi; traumatologi;

    Sammanfattning : Intestinal ischemia and reperfusion (I/R) is a potentially life-threatening condition, sometimes leading to a systemic inflammatory response and the potential development of the multiple organ dysfunction syndrome. The overall aim of the thesis was to study the effects of intestinal I/R on pulmonary function with special emphasis on removal of excess alveolar fluid, pulmonary endothelial barrier permeability, leukocyte accumulation and function, and possible therapeutic strategies to prevent the development of pulmonary injury following intestinal I/R. LÄS MER

  2. 2. Hepatic ischemia-reperfusion injury

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Clinical Science, Intervention and Technology

    Författare :Melroy Alistair D'Souza; Karolinska Institutet.; Karolinska Institutet.; [2020]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Hepatic ischemia-reperfusion (I/R) injury is a complex phenomenon occuring in response to interruption of the liver’s blood and oxygen supply and the subsequent restoration of blood flow and tissue oxygenation. Techniques to reduce blood loss and other intra-operative manoeuvers during liver resection can cause hepatic I/R injury. LÄS MER

  3. 3. Renal Ischemia/Reperfusion Injury in Diabetes Experimental Studies in the Rat

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jan Melin; Bengt Rippe; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical sciences; diabetes mellitus; ischemia reperfusion; rat; end-stage renal disease; inflammation; fibrosis; hyaluronan; CD44; treatment; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Diabetes mellitus (DM) is one of the leading causes of end stage renal failure. An increased susceptibility to renal ischemia/reperfusion (I/R)-injury was found in DM rats. Unilateral renal ischemia for as short as 20 minutes led to an irreversible progressive injury in DM kidneys, whereas the injury in non-DM kidneys was almost reversible. LÄS MER

  4. 4. Myocardial ischemia and reperfusion injury, clinical and experimental studies

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Karin Åström-Olsson; Göteborgs universitet.; Gothenburg University.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; myocardium; ischemia; reperfusion injury; FKBP12; FKBP12.6;

    Sammanfattning : Acute myocardial infarction is the consequence of an occluded nutrient coronary artery. Reperfusion reduces infarct size and enhances the rate of survival. But reperfusion may also, in itself, cause reversible injury, stunning and arrhythmias, as well as irreversible lethal reperfusion injury. LÄS MER

  5. 5. Pharmacological interventions against myocardial ischemia and reperfusion injury

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Lars O Karlsson; Göteborgs universitet.; Gothenburg University.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Myocardial reperfusion injury; opioids; cyclosporine A;

    Sammanfattning : Background: Ischaemic heart disease is the leading cause of death in the industrialised world. Although the concept of early restoration of coronary blood-flow constitutes an important factor to reduce the injury caused by myocardial ischaemia, reperfusion in itself can aggravate the damage to myocardial tissue, a phenomenon denoted myocardial reperfusion injury. LÄS MER