Sökning: "P fimbriae"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden P fimbriae.

1. 1. Mechanisms of P fimbriae cell activation

   Författare :Maria Hedlund; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 1 fimbriae; LPS; glycosphingolipids; ceramide; E. coli; P fimbriae; mucosa; cytokines; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : Microbial attachment to host cells plays a central role in the induction of inflammatory responses and the production of the disease. Uropathogenic Gram negative bacteria carry surface lectins that specifically recognize oligosaccharide receptor epitopes expressed on glycolipids or glycoproteins. LÄS MER

3. 2. Febrile Urinary Tract Infection: P fimbriae, Innate Host Response and Bacteremia

   Författare :Gisela Otto; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prsGJ96; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; papGIA2; antibiotic therapy; urine; chemokine; interleukin-6; host response; P fimbriae; bacteremia; febrile urinary tract infection; Escherichia coli;

   Sammanfattning : Urinary tract infections (UTI) are among the most common human infections, and febrile UTI with bacteremia the most severe form. The relation between bacteria and host decides disease severity. The dominating uropathogen is Escherichia coli (E. coli). LÄS MER

4. 3. Escherichia coli Fimbriae, Bacterial Persistence and Host Response Induction in the Human Urinary Tract

   Författare :Göran Bergsten; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; bacteriology; Microbiology; IL-8; IL-6; neutrophils; GFP; mucosal host response; Type 1 fimbriae; P fimbriae; adherence; virulence factors; regulation; deliberate colonisation; Escherichia coli 83972; Urinary tract infection; asymptomatic bacteriuria;

   Sammanfattning : Urinary tract infections (UTI) are among the most common bacterial infections in humans. Symptomatic UTIs may be acute, recurrent or chronic but the most frequent form of UTI is asymptomatic bacteruria (ABU). In ABU, the mucosa remains inert, despite the presence of large bacterial numbers in urine. LÄS MER

5. 4. The role of P fimbriae for Escherichia coli establishment and mucosal inflammation in the human urinary tract

   Författare :Björn Wullt; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; asymptomatic bacteriuria; urinary tract infections; deliberate colonization; E. coli 83972; P-fimbriae; Mucosal host response; IL-6; IL-8; neutrophils; regulation.; GFP; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : Bacterial adhesion to the bladder mucosa is a critical step for the establishment of Escherichia coli bacteriuria. The P-fimbriae, encoded by the pap gene cluster, are considered as virulence factors but the mechanisms have been debated. This study defined the roles for P fimbriation during the early colonization of the human urinary tract. LÄS MER

7. 5. Molecular determinants of disease severity in urinary tract infection

   Författare :Ines Ambite; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Asymptomatic bacteriuria; urinary tract infection; acute pyelonephritis; cystitis; Escherichia coli 83972; host response; NlpD; RNA Polymerase II; transcription regulation; inflammasome; Il-1β; ASC; NLRP-3; hyper-inflammatory disorder; MMP-7; IL-1RA; genetic susceptibility; IRF-7; siRNA therapy; P fimbriae; type 1 fimbriae;

   Sammanfattning : In the urinary tract, Escherichia coli infection may result in life-threatening disease, or asymptomatic bacterial carriage, comparable to bacterial commensalism in the gut. Pathogenic strains trigger a disease provoking host response which differs depending on the infected organ. LÄS MER