Sökning: "virulence regulation"
Visar resultat 16 - 20 av 86 avhandlingar innehållade orden virulence regulation.
16. Meticulous control of the T3SS of Yersinia is essential for full virulence
Sammanfattning : The type III secretion system (T3SS) of pathogenic Yersinia pseudotuberculosis is involved in virulence. The syringe-like secretion system spans both bacterial membranes and is responsible for the ability of Yersinia to transfer toxic proteins (Yop proteins) into the eukaryotic target cell. LÄS MER
17. Timing and targeting of Type III secretion translocation of virulence effectors in Yersinia
Sammanfattning : The Type III secretion system (T3SS) is an important virulence mechanism that allows pathogenic bacteria to translocate virulence effectors directly into the cytoplasm of eukaryotic host cells to manipulate the host cells in favor of the pathogen. Enteropathogenic Yersinia pseudotuberculosis use a T3SS to translocate effectors, Yops, that prevent phagocytosis by immune cells, and is largely dependent on it to establish and sustain an infection in the lymphoid tissues of a mammalian host. LÄS MER
18. Biogenesis, function and regulation of the type III secretion translocon of Yersinia pseudotuberculosis
Sammanfattning : Many Gram negative bacteria use type III secretion systems to cross-talk with eukaryotic cells. Type III secretion system assembly and function is tightly regulated. LÄS MER
19. Regulation of virulence gene expression in Staphylococcus aureus
Sammanfattning : The pathogenic bacterium Staphylococcus aureus has the ability to cause a wide variety of human diseases, ranging from superficial abscesses and wound infections to deep and systemic infections such as osteomyelitis, endocarditis and septicaemia. The ability to cause disease has been attributed to a large number of toxins and digesting enzymes as well as to proteins at the bacterial surface that bind various host molecules. LÄS MER
20. Role of the Yersinia protein YopK in microbe-host interactions
Sammanfattning : There are three human pathogenic species of the genus Yersiniae: Yersinia pestis, Yersinia enterocolitica, and Yersinia pseudotuberculosis. To cause disease, these strains inhibit several key innate defense mechanisms, including phagocytosis, the critical process for bacterial clearance. LÄS MER