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Visar resultat 1 - 5 av 11 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Diabetes and cognitive functioning : the role of age and comorbidity

   Författare :Erik Nilsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Type 2 diabetes; cognition; cognitive support; glycated hemoglobin; Alzheimer s disease; adult; elderly; population-based study; out-patient; impending death; preclinical dementia; MMSE.;

   Sammanfattning : This thesis deals with the influence of type 2 diabetes on cognitive function in adulthood and very old age. The effects of diabetes are studied both in populations free from dementia, and in a clinical Alzheimer's disease population. LÄS MER

3. 2. Epidemiological aspects of cardiovascular morbidity and mortality among individuals with diabetes: the relative importance of cardiovascular risk factors

   Författare :Aidin Rawshani; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes mellitus; Cardiovascular medicine; Epidemiology; Observational studies; Heart failure; Cardiovascular disease; Mortality; Type 1 diabetes mellitus; Type 2 diabetes mellitus; Machine learning;

   Sammanfattning : Background: Long-term trends of cardiovascular complications and death among patients with diabetes have not been studied extensively. In addition, we aimed to examine the effect of multifactorial risk factor control, as well as optimal levels- and relative importance of cardiovascular risk factors, in patients with type 1 diabetes and type 2 diabetes. LÄS MER

4. 3. Semi-mechanistic models of glucose homeostasis and disease progression in type 2 diabetes

   Författare :Steve Choy; Maria Kjellsson; Mats Karlsson; Willem de Winter; Andrea Mari; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics; pharmacodynamics; pharmacometrics; glucose homeostasis; insulin; type 2 diabetes; obesity; weight; visceral adipose tissue; HbA1c; non-linear mixed effects; modelling; disease progression; ZDSD rats; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by consistently high blood glucose, resulting from a combination of insulin resistance and reduced capacity of β-cells to secret insulin. While the exact causes of T2DM is yet unknown, obesity is known to be a major risk factor as well as co-morbidity for T2DM. LÄS MER

5. 4. Trait anxiety as a determinant of psychological test results

   Författare :Roger Persson; Institutionen för psykologi; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Medicine human and vertebrates ; Environmental health; industrial medicine; Occupational health; work stress; toxic encephalopathy; symptom reporting; neuropsychological testing; organic solvents; repression; psychological methods; social desirability; anxiety; Personality traits; Medicin människa och djur ; Miljömedicin; arbetsmiljömedicin; Yrkesmedicin;

   Sammanfattning : This thesis deals with the problem of interpreting test scores. The intention has been to explore and elucidate the effects of trait anxiety on test scores that have been obtained in applied research settings. LÄS MER

7. 5. On cardiovascular complications in people with type 2 diabetes : Aspects of incretin-based therapy and glycemic control

   Författare :Irene Santos Pardo; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Hyperglycemia, insulin resistance, and the presence of advanced glycation end products are key features of type 2 diabetes (T2DM) and the leading mechanisms behind the increased cardiovascular risk observed in people with this condition. Percutaneous coronary revascularization has been associated with higher risk of stent failure in people with diabetes mellitus (DM), having greater risk of both in-stent restenosis (ISR) and stent thrombosis (ST). LÄS MER