Sökning: "preclinical dementia"

Visar resultat 1 - 5 av 28 avhandlingar innehållade orden preclinical dementia.

  1. 1. Dementia Proteomics

    Författare :Julia Remnestål; Peter Nilsson; Anna Månberg; Pieter Jelle Visser; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dementia; Proteomics; Alzheimer s disease; Frontotemporal dementia; Antibody array; Suspension bead array; Cerebrospinal fluid; Protein profiling; Biomarker discovery; Bioteknologi; Biotechnology;

    Sammanfattning : The term dementia encompass a number of conditions arising as a consequence of tissue degeneration in the brain. This degeneration is caused by molecular events occurring on a cellular level including inflammation, defective waste disposal and accumulation of insoluble proteins and peptides. LÄS MER

  3. 2. Neurodegenerative Biomarkers in Healthy Elderly - with special reference to the preclinical pattern of biological and cognitive markers for Alzheimer’s disease

    Författare :Erik Stomrud; Klinisk minnesforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cerebral blood flow; EEG; phosphorylated tau protein; amyloid beta protein; tau protein; cerebrospinal fluid; biomarkers; preclinical Alzheimer s disease; Alzheimer s disease; MCI; dementia; SPECT; memory; cognition; early diagnosis; control groups;

    Sammanfattning : Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by tau and amyloid brain pathology. With the gradual degeneration of neurons, cognitive symptoms will arise and the affected individual will eventually develop AD dementia. LÄS MER

  4. 3. Subjective cognitive decline in memory clinic patients - characteristics and clinical relevance : Results from Sahlgrenska University Hospital Memory Clinic in Mölndal

    Författare :Marie Eckerström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cognition; self-assessment; memory; mild cognitive impairment; subjective cognitive decline; dementia; Alzheimer s disease; preclinical AD; stress; depressive symptoms; memory clinic;

    Sammanfattning : Subjective cognitive decline (SCD) refers to concerns – symptoms - regarding one’s cognitive functioning, in the absence of objective evidence of impairment. SCD has been described as a possible stage preceding mild cognitive impairment (MCI) and dementia. LÄS MER

  5. 4. Understanding preclinical dementia : early detection of dementia through cognitive and biological markers

    Författare :Nicola Maria Payton; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Dementia is becoming a growing healthcare crisis, therefore identifying individuals at risk or in the earliest stages of dementia is essential if prevention or disease modification is to be achieved. The objective of this thesis was to examine cognitive performance and decline during the preclinical phase and explore the ability of cognitive and biological markers to identify those at risk of future dementia. LÄS MER

  7. 5. Cognitive functioning in the preclinical stages of Alzheimer's disease and vascular dementia

    Författare :Sari Jones; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cognition; preclinical; Alzheimer s disease; vascular dementia; neuropsychology;

    Sammanfattning : This doctoral thesis concerns cognitive functioning in the preclinical stages of Alzheimer's disease (AD) and vascular dementia (VaD). It is based on five empirical studies using data from the Kungsholmen Project, a longitudinal population-based study of aging and dementia targeting persons 75 years and older, living in the Kungsholmen District in Stockholm, Sweden. LÄS MER