Sökning: "Type 2 diabetes"
Visar resultat 1 - 5 av 800 avhandlingar innehållade orden Type 2 diabetes.
- Detta är en avhandling från Haiyan Li, Wallenberg Laboratory ing 46, Malmö University Hospital, 20502 Malmö, Sweden
Sammanfattning : There are two major types of diabetes, type 1 and type 2 diabetes. Similarly characterized by hyperglycaemia and long term micro- and macrovascular complications, type 1 and type 2 diabetes have different underlying pathophysiologic processes. In Scandinavia, type 1 diabetes is common; type 2 diabetes accounts for 85% of all cases with diabetes. LÄS MER
2. Pharmacometrics Modelling in Type 2 Diabetes Mellitus Implications on Study Design and Diabetes Disease ProgressionDetta är en avhandling från Uppsala : Acta Universitatis Upsaliensis
Sammanfattning : Pharmacometric modelling is widely used in many aspects related to type 2 diabetes mellitus (T2DM), for instance in the anti-diabetes drug development, and in quantifying the disease progression of T2DM.The aim of this thesis were to improve the design of early phase anti-diabetes drug development studies with the focus on the power to identify mechanism of drug action (MoA), and to characterize and quantify the progression from prediabetes to overt diabetes, both the natural progression and the progression with diet and exercise interventions, using pharmacometrics modelling. LÄS MER
- Detta är en avhandling från Göteborgs universitet
Sammanfattning : Worldwide, 1% of all live born children are born with a congenital heart disease (CHD) and currently >95% reach adulthood due to better diagnostics and medical care. At the same time, Diabetes Mellitus (DM), type 1 (T1DM) and type 2 (T2DM), is increasing worldwide. LÄS MER
4. Antigen-specific islet antibodies: prediction of beta cell failure and differentiation between Type 1 and Type 2 diabetesDetta är en avhandling från Henrik Borg, Wallenberg Laboratory, Entrance 46 2nd floor, Malmö University Hospital, SE-205 02 Malmö, Sweden
Sammanfattning : Autoantibodies against glutamic acid decarboxylase (GADA), protein tyrosine-phosphatase-like protein (IAÐ2A), and/or pancreatic islet cells (ICA) are autoimmune markers usually present at diagnosis of Type 1 diabetes. Type 1 diabetes is therefore in general believed to be caused by an immune-mediated beta cell destruction. LÄS MER
- Detta är en avhandling från Henrik Borg, Wallenberg Laboratory, Entrance 46 2nd floor, Malmö University Hospital, SE-205 02 Malmö, Sweden
Sammanfattning : Diabetes is a heterogeneous disease influenced by both environmental and genetic factors. Maturity-onset diabetes of the young (MODY) is considered as a subform of Type 2 diabetes, which is inherited in an autosomal dominant fashion and expressed at childhood or early adult life. LÄS MER