Sökning: "obesity"

Visar resultat 1 - 5 av 914 avhandlingar innehållade ordet obesity.

  1. 1. Obesity Genetics : Functional Aspects of Four Genetic Loci Associated with Obesity and Body Mass

    Författare :Mathias Rask-Andersen; Helgi Schiöth; Ingrid Dahlman; Uppsala universitet; []

    Sammanfattning : Obesity is a complex disorder which has reached epidemic proportions in many parts of the world. Twin studies have demonstrated a high heritability for obesity. The subsequent appli-cation of genome wide association studies (GWAS) in the last decade have identified at least 32 genetic loci associated with body mass and obesity. LÄS MER

  2. 2. Obesity and Increased Susceptibility : Role of FTO and MGAT1 Genetic Variants

    Författare :Josefin A Jacobsson; Robert Fredriksson; Helgi B Schiöth; Sadaf Farooqi; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; BMI; SNP; haplotype; association study; FTO; MGAT1; Pharmacology; Farmakologi; Farmakologi; Pharmacology;

    Sammanfattning : Obesity is a complex and a highly individualized disease and the molecular mechanisms behind this disorder need to be better elucidated. Identification of genes and genetic variants that are involved provide opportunities to establish a genetic understanding of the disease. LÄS MER

  3. 3. Pathogenesis of Obesity and Effects of Treatment. Clinical and Molecular Studies on Body Fat, Energy Balance, and Weight Loss

    Författare :Anders Gummesson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :Obesity; Adipose tissue; Obesity treatment; Energy balance; Visceral obesity; Weight loss; Cancer; Human studies;

    Sammanfattning : Obesity is common and related to many health problems including various forms of cancer. The condition arises from the imbalance between food intake and energy expenditure, and is strongly influenced by genetic factors. LÄS MER

  4. 4. Environmental Contaminants and Obesity

    Författare :Monika Rönn; P. Monica Lind; Lars Lind; Jan Örberg; Merete Eggesbø; Uppsala universitet; []
    Nyckelord :Fischer 344; rat; obesity; adipose tissue; persistent organic pollutants; POPs; bisphenol A; BPA; pesticides; dioxin; PCB; DDT; apo A-I; adiponectin; leptin; ghrelin;

    Sammanfattning : Obesity is a worldwide problem affecting both children and adults. Genetic, physiological, environmental, psychological, social and economic factors interact in varying degrees, influencing body weight and fat distribution and the progress of obesity. LÄS MER

  5. 5. Testing Pills, Enacting Obesity : The work of localizing tools in a clinical trial

    Författare :Petra Jonvallen; Boel Berner; Claes-Fredrik Helgesson; Linköpings universitet; []
    Nyckelord :SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Invisible work; contract research organisation; standardization; articulation work; production tasks; enactment; evidence based medicine; clinical trials; clinical research protocol; rationalizing tools; obesity; pharmaceutical production; clinical practice; medicalisation; Övervikt; klinisk prövning; Technology and social change; Teknik och social förändring; Genus och teknik; Gender and Technology;

    Sammanfattning : This study examines tools and practices involved in a large scale and multi-sited clinical trial of a potential drug against obesity. Two tools are in focus: a clinical research protocol and a computer control system. LÄS MER