Sökning: "Tumor immunology"

Visar resultat 11 - 15 av 112 avhandlingar innehållade orden Tumor immunology.

  1. 11. Monoclonal antibodies against carcinoembryonic antigen and their use in tumor diagnosis

    Författare :Anders Hedin; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : A new CEA-related substance, (CEAlow) was isolated from liver metastases of colorectal cancer. Purified CEAlow was homogeneous by several physico-chemical criteria. It had an apparent molecular weight of 125,000. 2/9 monkey anti-CEA sera gave a spur with CEA over CEAlow in immunodiffusion. LÄS MER

  3. 12. Immunological studies of human bladder cancer (TCC) : analysis of the immune response and the use of anti-TCC antibodies for tumor localization

    Författare :Yngve Hansson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  4. 13. Hormonal regulation of liver and tumor growth

    Författare :Ville Wallenius; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver; cytokine; interleukin-6; tumor necrosis factor; primary liver growth promoter; cyproterone acetate; nafenopin; hepatocyte growth factor; HGF receptor; tumor; sarcoma; N-terminal; truncated;

    Sammanfattning : The aims of this thesis were to investigate the regulatory functions of interleukin-6 (IL-6) and tumor necrosis factor-a (TNF-a) on liver growth, and the importance of hepatocyte growth factor (HGF) and the HGF receptor (Met) for growth of mesenchyme-derived tumors. The studies on different types of liver growth, measured as weight, DNA and protein content, and DNA synthesis, were performed on mice lacking the IL-6 or the TNF receptor-1 gene back-crossed to the C57bl/6 strain. LÄS MER

  5. 14. Immunological Checkpoint Blockade and TLR Stimulation for Improved Cancer Therapy

    Författare :Sara Mangsbo; Thomas Tötterman; Angelica Loskog; Rolf Kiessling; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CpG ODNs; TLR-9; CTLA-4; PD-1; PD-L1; B7. H1; immunotherapy; checkpoint blockade; bladder cancer; cancer; complement; TLRs; Compstatin; properdin; C3; experimental animal model; whole blood loop system; combination therapies; Clinical immunology; Klinisk immunologi; Tumour immunology; Tumörimmunologi; immunologi; Immunology;

    Sammanfattning : This thesis concerns the investigation of novel immunotherapies for cancer eradication. CpG therapy was used in order to target antigen-presenting cells (APCs), facilitating antigen presentation and activation of T cells. LÄS MER

  7. 15. Novel methods of malignant brain tumor treatment utilizing the tumor microenvironment

    Författare :Jan Kopecky; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain tumors; Glioblastoma; Medulloblastoma; Convection-enhanced delivery; Antisecretory factor; AF16; Salovum; Macrophages; Immunology; Cancer; CD24; Siglec10; Antiphagocytic signaling;

    Sammanfattning : Malignant brain tumors constitute a disaster in the lives of patients, either in the form of extremely low survival in glioblastoma, or the serious long-term adverse effects of therapy in medulloblastoma. These two tumor types represent the most common malignant brain entities in adults and children, respectively. LÄS MER