Sökning: "experimental animal model"

Visar resultat 1 - 5 av 306 avhandlingar innehållade orden experimental animal model.

  1. 1. On optical methods for intracerebral measurements during stereotactic and functional neurosurgery Experimental studies

    Detta är en avhandling från Institutionen för medicinsk teknik

    Författare :Johan Antonsson; Karin Wårdell; Lars-Erik Augustinsson; [2007]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Laser Doppler perfusion monitoring; Diffuse reflectance spectroscopy; Functional and stereotactic neurosurgery; TECHNOLOGY Other technology Medical engineering; TEKNIKVETENSKAP Övriga teknikvetenskaper Medicinsk teknik;

    Sammanfattning : Radio frequency (RF) lesioning and deep brain stimulation (DBS) are the two prevailing surgical treatments for movement disorders within the field of stereotactic and functional neurosurgery. For RF-lesioning, a small volume of brain tissue is coagulated and knowledge of the lesion size and growth is of great importance for the safety and outcome of the procedure. LÄS MER

  2. 2. Topical anesthesia of the tympanic membrane an experimental animal study

    Detta är en avhandling från Institutionen för medicinsk teknik

    Författare :Sten-Hermann Schmidt; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Topical anesthesia; middle ear; tympanic membrane; cochlea; collagen fibres; lidocaine; 96 % phenol; Bonain s liquid; auditory brainstem response; ototoxicity; cytocochleogram; scanning electron microscopy; rat; guinea pig;

    Sammanfattning : Myringotomy plays an important role in otological therapy. The procedure requires an efficient anesthesia, which can be obtained without general anesthesia. However, the use of local anesthetics on the tympanic membrane (TM) has been abandoned in many places, as general anesthesia has been readily available. LÄS MER

  3. 3. The Immune Response to One-Lung Ventilation Clinical and Experimental Studies

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Thomas Schilling; Göran Hedenstierna; Hans Hedenström; Thomas Hachenberg; Sven-Erik Ricksten; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; One-lung ventilation; open thoracic surgery; ventilation-induced lung injury; alveolar immune response; bronchoalveolar lavage; propofol; desflurane; cytokines; animal model; mRNA; RT-PCR; INTERDISCIPLINARY RESEARCH AREAS Caring sciences Medical laboratory science; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN Vårdvetenskap Medicinsk laboratorievetenskap; anestesiologi; Anaesthesiology;

    Sammanfattning : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. LÄS MER

  4. 4. Experimental porcine models of retinal ischemia

    Detta är en avhandling från Ophthalmology (Lund), Lund University

    Författare :Håkan Morén; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retinal ischemia; animal model; multifocal electroretinography; intraarterial coiling; retinal vasculature;

    Sammanfattning : Retinal ischaemia resulting from e.g. diabetes, vein thrombosis or arterial occlusion, is one of the major causes of visual impairment and blindness. Although new methods of treatment are being developed, there is still a need for more effective pharmacological forms of treatment. LÄS MER

  5. 5. Pathophysiological, Inflammatory and Haemostatic Responses to Various Endotoxaemic Patterns An Experimental Study in the Pig

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Miklós Lipcsey; Uppsala universitet.; [2006]
    Nyckelord :Anaesthesiology and intensive care; sepsis; animal model; cytokines; isoprostanes; endotoxic shock; pig; Anestesiologi och intensivvård;

    Sammanfattning : Septic shock is frequently seen in intensive care units and is associated with significant mortality. Endotoxin – a major mediator of the pathophysiologic responses – is released during lysis of Gram-negative bacteria. These responses can be mimicked in the endotoxaemic pig. LÄS MER