Sökning: "Brain tumors"

Visar resultat 1 - 5 av 138 avhandlingar innehållade orden Brain tumors.

  1. 1. Genes and brain tumors

    Författare :Maral Adel Fahmideh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Although brain tumors are rare and combined with other nervous system tumors account for ~ 2% of all cancers, they are the second most common type of pediatric cancer. The etiology of brain tumors, known as multifactorial traits, is poorly understood. LÄS MER

  2. 2. Proton Magnetic Resonance Spectroscopy in Brain Tumors - Clinical Applications

    Författare :Isabella Björkman-Burtscher; Lund Diagnostisk radiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiology; Clinical physics; Localization; Abscess; Brain; Tumor; Spectroscopy; Magnetic Resonance; tomography; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

    Sammanfattning : Aims: · to present a test phantom and test method for evaluation of proton magnetic resonance spectroscopy (1H-MRS) single volume localization techniques regarding signal contamination; · to describe the introduction of 1H-MRS in the daily routine of a standard MR-unit; · to evaluate the possibilities offered by 1H-MRS to improve preoperative diagnostic accuracy in patients scheduled for stereotactic biopsy of intracranial mass lesions; · to evaluate the possibilities offered by 1H-MRS to improve diagnostics and therapy control in patients with brain abscesses; · to test the hypothesis that 1H-MRS might be useful for differentiation of brain tumors, based on metabolic changes in tissue across brain lesions or surrounding tissue. Results and conclusions: · The test phantom and test method allow quality assessment with good reproducibility. LÄS MER

  3. 3. Experimental brain tumors, dendritic cells and immunotherapy

    Författare :Shorena Janelidze; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dendritic cell; interferon-γ; immunotherapy; Brain tumor;

    Sammanfattning : Malignant astrocytomas are the most common primary tumors of the adult central nervous system. Surgical resection of tumor mass in combination with radiotherapy and chemotherapy is only palliative and there is a clear need for new and more effective therapeutic strategies. LÄS MER

  4. 4. Immunotherapy and COX-2 inhibition against malignant brain tumors

    Författare :Sofia Eberstål; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malignant brain tumors; immunotherapy; IFN-γ; GM-CSF; COX-2 inhibition;

    Sammanfattning : Glioblastoma multiforme (GBM) is the most common primary brain tumor in the central nervous system and the prognosis is very poor despite conventional therapies including surgery, chemo- and radiotherapy. Peripheral vaccination with irradiated tumor cells represent a novel therapy that targets both dividing and non-dividing tumor cells and minimizes the risk of therapy resistance by presenting multiple tumor antigens. LÄS MER

  5. 5. Cognitive Deficits Reflecting Diffuse and Focal Brain Lesions Caused by Slow Growing Brain Tumors - Low-grade Gliomas

    Författare :Lena Ek; Ove Almkvist; Anja Smits; Hans Samuelsson; Stockholms universitet; []
    Nyckelord :SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; Cognition; low-grade glioma; brain tumor; diffuse brain injury; neuropsychological tests; Psychology; Psykologi; psykologi; Psychology;

    Sammanfattning : The overall purpose was to characterize the impact that low-grade glioma (LGG) – a type of slowly growing brain tumor – has on cognitive functions. Paper I was an in-depth analysis of cognitive dysfunction of patients with histological proven LGG. LÄS MER