Sökning: "immunotherapy"

Visar resultat 1 - 5 av 198 avhandlingar innehållade ordet immunotherapy.

  1. 1. Cancer Immunotherapy A Preclinical Study of Urinary Bladder Cancer

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Christina Ninalga; Uppsala universitet.; [2006]
    Nyckelord :Medicine; immunotherapy; bladder carcinoma; cancer; CpG ODNs; Adenoviral vector; CD40L; TRANCE; Lymphotactin; IL2; IL15; Medicin;

    Sammanfattning : Bacillus Calmette Guérin (BCG), or attenuated Mycobacterium bovis, is the gold standard of immunotherapy in the clinic to treat superficial bladder cancer. However, setbacks remain due to a high recurrence rate, side effects, and BCG-refractory disease. LÄS MER

  2. 2. Cancer Immunotherapy Evolving Oncolytic viruses and CAR T-cells

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mohanraj Ramachandran; Uppsala universitet.; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncolytic virus; Adenovirus; Semliki Forest virus; Cancer immunology; Chimeric antigen receptor T-cells; Immunologi; Immunology; Oncology; Onkologi; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : In the last decade cancer immunotherapy has taken huge strides forward from bench to bedside and being approved as drugs. Cancer immunotherapy harnesses the power of patient’s own immune system to fight cancer. LÄS MER

  3. 3. Immunotherapy of children with rhinoconjunctivitis due to birch pollinosis

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Christian Möller; Umeå universitet.; [1986]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Birch pollinosis; Conjunctival provocation test; Crossed radioimmunoelectrophoresis; Crossreactivity tree pollens; Immunotherapy; Oral immunotherapy; Polyethyleneglycol absorption; Pollen counts; Rhinoconjunctivitis; Symptom score;

    Sammanfattning : In this investigation of immunotherapy (IT) children 6-16 years old with rhinoconjunctivitis due to birch polli­nosis were included.I. Methodological studies. To monitor IT a reliable provocation test is desirable. LÄS MER

  4. 4. Immunological mechanisms involved in seasonal pollen allergy and allergen-specific immunotherapy

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Robert Movérare; Uppsala universitet.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical sciences; Allergy; birch pollen; IFN-g; IgE; IgG; IgG4; IL-4; IL-5; IL-10; IL-13; immunotherapy; PBMC; rush immunotherapy; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; lungmedicin; Lung Medicine;

    Sammanfattning : Th1/Th2-like T-cell responses were studied by stimulating peripheral blood mononuclear cells (PBMCs) with allergens or antigens followed by restimulation with mitogens to induce high cytokine synthesis. Allergen-stimulation in vitro induced Th2-skewed cytokine synthesis by PBMCs from birch-pollen-allergic patients. LÄS MER

  5. 5. Immunotherapy and immunosuppression in myeloid leukemia

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Alexander Hallner; Göteborgs universitet.; Gothenburg University.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Natural killer cells; acute myeloid leukemia; histamine dihydrochloride; immunotherapy; reactive oxygen species; chronic myelomonocytic leukemia; NK cell education; NKG2A; HLA; KIR;

    Sammanfattning : Acute myeloid leukemia (AML) and chronic myelomonocytic leukemia (CMML) are potentially life-threatening blood cancers characterized by the expansion of malignant myeloid cells in bone marrow and other organs. This thesis aimed at contributing to the understanding of the role of natural killer (NK) cells in AML and CMML with focus on the potential impact of the immunosuppression exerted by reactive oxygen species (ROS) formed by the myeloid cell NOX2 enzyme. LÄS MER