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Visar resultat 11 - 15 av 62 avhandlingar innehållade ordet öar.

  1. 11. Study of DNA methylation in human pancreatic islets

    Författare :Elin Hall; Diabetes - epigenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 2 diabetes; epigenetics; DNA mehtylation; human pancreatic islets; insulin secretion;

    Sammanfattning : Today type 2 diabetes is a common disease with a worldwide prevalence of 8.3%. The disease is characterised by hyperglycaemia which is a result of insufficient insulin secretion from the beta-cells in the pancreatic islets as well as an insulin resistance seen in the target tissues. LÄS MER

  3. 12. The threat from non indigenous species - ecosystem vulnerability, global distribution and co-occurrence with other major threats

    Författare :Helena Berglund; Biodiversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; threats; distribution range; isolation; endemism; invasions; invaders; vulnerability; non indigenous species; rarity; threatened species;

    Sammanfattning : We live in a globalised world where people and goods travel large distances. Various species are brought along on these journeys, intentionally or as hitchhikers. Some of these species establish populations in regions to which they could not have spread without human assistance, and where they are considered to be non indigenous species (NIS). LÄS MER

  4. 13. Electrophysiology of pancreatic A-, B- and D-cells studied in intact mouse islets of Langerhans

    Författare :Sven Göpel; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; somatostatin; glucagon; insulin; patch-clamp; membrane potential; Pancreatic islet; ion channel; diabetes; Physiology; Fysiologi;

    Sammanfattning : Abstract The electrophysiological properties of insulin-secreting b-cells, glucagon-releasing a-cells and somatostation-producing d-cells in intact mouse pancreatic islets were investigated using the perforated patch whole-cell technique. It is demonstrated that it is possible to functionally identify the different cell types in situ. LÄS MER

  5. 14. Läskulturer. Lärare, elever och litteraturläsning i grundskolans mellanår

    Författare :Annette Ewald; Litteraturvetenskap; []
    Nyckelord :HUMANIORA; HUMANITIES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Humanities; upper elementary school; the teaching of literature; traditions of literature instruction; reading cultures; school ethnography; didactic subject research; Humaniora; General and comparative literature; Allmän och jämförande litteraturvetenskap; Pedagogy and didactics; Pedagogik; didaktik; school ethnography;

    Sammanfattning : This dissertation explores the teaching of literature in Swedish compulsory school. The aim of the study is to elucidate different approaches to literature instruction in upper elementary school (grades 4-6, pupils aged 10-13). LÄS MER

  7. 15. The Role of Phosphodiesterase 3B in the Regulation of Insulin Secretion

    Författare :Linda Härndahl; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; secreting systems; Endocrinology; beta-cell; diabetes; islet; PDE3B; cAMP;

    Sammanfattning : Pancreatic beta-cell dysfunction and insulin resistance are the two hallmarks of type 2 diabetes. An early sign of beta-cell dysfunction is impaired nutrient-induced insulin release. Several insulin secretagogues act by increasing the formation of intracellular cAMP. LÄS MER