Sökning: "Endocrinology"

Visar resultat 1 - 5 av 268 avhandlingar innehållade ordet Endocrinology.

  1. 1. Candidate Genes for Late Diabetic Complications

    Detta är en avhandling från Endocrinology

    Författare :Eero Lindholm; Lund University.; Lunds universitet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TNF; sekretion; LTA; Endocrinology; nephropathy; diabetes mellitus; retinopathy; neuropathy; genetic; UCP; diabetologi; AGER; MHc2TA; HLA-DQB1; Endokrinologi; secreting systems; diabetology;

    Sammanfattning : Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The new WHO criteria for classification of diabetes takes into account also clinical stages dividing the diabetic patients into noninsulin requiring (NIR), insulin requiring for control (IRC) and insulin requiring for survival (IRS) subgroups. LÄS MER

  2. 2. Heritability of blood pressure: monogenes and polygenes

    Detta är en avhandling från Diabetes and Endocrinology

    Författare :Cristiano Fava; Lund University.; Lunds universitet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Biomedicinska vetenskaper; Biomedical sciences; kidney; Adducin-1; CLC-kb; Gitelman syndrome; association; heritabilty; genetics; hypertension; Blood pressure; blood pressure variability; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : High blood pressure (BP) is associated with cardiovascular morbidity and mortality. Both genetic and environmental factors are implicated in BP homeostatsis and hypertension development. LÄS MER

  3. 3. Human glycogen synthase genes. Role in insulin resistance and hypoglycaemia

    Detta är en avhandling från Department of Endocrinology, Wallenberg laboratory, Malmö University Hospital

    Författare :Marju Orho-Melander; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mutation; GYS2; GYS1; glycogen synthase; glycogen; insulin resistance; hypoglycaemia; liver glycogen synthase deficiency; glycogen storage disease type 0; Type 2 diabetes; metabolic syndrome; expression; chromosome 19; 19q13.3; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Effective insulin-stimulated storage of excess glucose after a meal, and its rapid mobilisation in the fasting state provide basis of glucose homeostasis. Glycogen is the macromolecular storage form of glucose and glycogen synthase (GS) is the rate-limiting enzyme in glycogen synthesis. Skeletal muscle and liver are the major depots of glycogen. LÄS MER

  4. 4. Exploring Positional and Functional Candidate Genes for Type 2 Diabetes

    Detta är en avhandling från Lund University, Department of Clinical Sciences, Diabetes and Endocrinology, Malmö University Hospital

    Författare :Johan Holmkvist; Lund University.; Lunds universitet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi; MODY; type 2 diabetes; Endocrinology; calcium channel; insulin secretion; insulin; single nucleotide polymorphism SNP glucose; linkage disequilibrium; genetic association; genetics;

    Sammanfattning : Type 2 diabetes (T2D) is a complex, metabolic disorder characterized by hyperglycaemia because of defects in insulin secretion and sensitivity. The rapid increase in T2D is likely to reflect the influence of both genetic and environmental factors in disease development. However, the genetic aetiology of T2D remains largely unknown. LÄS MER

  5. 5. Genetic and immunological risk factors of gestational diabetes mellitus

    Detta är en avhandling från Lund University Department of Clinical Sciences Diabetes and Endocrinology Malmö University Hospital

    Författare :Nael Shaat; Lund University.; Lunds universitet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GDM; Association; genetics; gestational diabetes mellitus metabolic syndrome; MODY; type 1 diabetes; risk factors; type 2 diabetes; Endocrinology; diabetology; secreting systems; autoimmunity; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Gestational diabetes mellitus (GDM) is a heterogeneous disorder that is defined as carbohydrate intolerance with onset or first recognition during pregnancy. Impaired beta-cell function and insulin resistance are the hallmarks of GDM. LÄS MER