Sökning: "Linda Härndahl"

Hittade 1 avhandling innehållade orden Linda Härndahl.

1. 1. The Role of Phosphodiesterase 3B in the Regulation of Insulin Secretion

   Författare :Linda Härndahl; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; secreting systems; Endocrinology; beta-cell; diabetes; islet; PDE3B; cAMP;

   Sammanfattning : Pancreatic beta-cell dysfunction and insulin resistance are the two hallmarks of type 2 diabetes. An early sign of beta-cell dysfunction is impaired nutrient-induced insulin release. Several insulin secretagogues act by increasing the formation of intracellular cAMP. LÄS MER