Sökning: "Topical"

Visar resultat 11 - 15 av 183 avhandlingar innehållade ordet Topical.

  1. 11. Bisphosphonates for orthopedic applications. Studies in rat models

    Författare :Jörgen Åstrand; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Kirurgi; ortopedi; traumatologi; orthopaedics; Surgery; topical treatment; osteonecrosis; bone graft resorption; prosthetic loosening; Bisphosphonates; osteoclasts;

    Sammanfattning : Prosthetic loosening, bone graft resorption and osteonecrosis are examples of problems in orthopedic surgery caused by or augmented by bone resorption. Bone resorption is caused by osteoclasts. Osteoclasts can be inactivated with biphosphonates, a drug in clinical use against osteoporosis and osteolytic tumors. LÄS MER

  2. 12. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

    Författare :Lukas Boge; Martin Andersson; Lovisa Ringstad; RISE; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid crystals; liquid crystalline nanoparticles; cubosome; hexosome; phase behavior; antimicrobial peptide; AMP; glycerol monooleate; proteolysis; antimicrobial effect; antimicrobial resistance; bacterial membrane; membrane interaction; infection; topical delivery; pulmonary delivery;

    Sammanfattning : The development of antimicrobial resistance is a great challenge within health sectors worldwide. Thus, demand for new, efficient treatments is urgent in order to treat various bacterial infections. Antimicrobial peptides (AMPs) are a group of antibiotics that have gained more and more attraction in the past decade. LÄS MER

  3. 13. Corneal stromal cell responses to traumatic wounds and topical treatments

    Författare :Marina Kulikovska; Per Fagerholm; Neil Lagali; Anders Behndig; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Background. The cornea has unique anatomic, cellular, molecular, and functional features that lead to important mechanistic differences in the process of repair in comparison with what occurs in skin and other organs. The first observable stromal response in corneal wound healing is keratocyte apoptosis. LÄS MER

  4. 14. Avtalets räckvidd I : Om avtals tredjemansverkningar, särskilt vid tredjemansavtal och direktkrav

    Författare :Oskar Mossberg; Joel Samuelsson; Laila Zackariasson; Juha Karhu; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; contract law; third parties; third party effects; third party contracts; direct claims; law and literature; law and rhetoric; law and humanities; topical jurisprudence; rhetorical hermeneutics; avtalsrätt; tredjemansavtal; direktkrav; retorisk hermeneutik; topisk retorik; Civil Law; Civilrätt;

    Sammanfattning : The idea that a contract should affect other people than the parties has seemingly always been a provocative notion. A contract binds the contracting parties – and only them – together in a legal relationship, and yet according to contemporary law a contract can have various legal effects for third parties, i.e. non-parties. LÄS MER

  5. 15. Tactile Perception : Role of Friction and Texture

    Författare :Lisa Skedung; Mark Rutland; Siegfried Derler; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; human skin; tactile friction; finger friction; skin friction; skin tribology; biotribology; tactile perception; haptic perception; psychophysics; haptics; surface roughness; surface texture; contact area; nanostructure; model surfaces; surface wrinkling; printing paper; tissue paper; magnitude estimation; multidimensional scaling; tactile threshold; psychophysical relations; smoothness; coolness; coarseness; softness; force sensor; skin lipids; topical formulations; skin creams; taktil friktion; fingerfriktion; hudfriktion; hudtribologi; biotribologi; taktil perception; psykofysik; haptik; ytråhet; ytstruktur; ytveckning; nanostruktur; kontaktarea; modellytor; friktionskoefficient; kraftmätare; bestruket papper; obestruket papper; tryckpapper; mjukpapper; multidimensionell skalning; magnitud estimation; taktilt tröskelvärde; lenhet; mjukhet; svalhet; strävhet; hudlipider; topikala beredningar; hudkräm;

    Sammanfattning : Tactile perception is considered an important contributor to the overall consumer experience of a product. However, what physical properties that create the specifics of tactile perception, are still not completely understood. LÄS MER