Sökning: "Topical"

Visar resultat 21 - 25 av 183 avhandlingar innehållade ordet Topical.

  1. 21. A study on the vascular effects of prostaglandin F2α[ and latanaprost in the eye with special reference to the surface hyperaemia after topical administration

    Författare :Maria Astin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Prostaglandin F2a; Prostaglandin F2a-isopropyl ester; latanoprost; latanoprost acid; ocularhyperaemia; blood flow; sensory nerves; veins; arteries; nitric oxide; substance P; CGRP; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Pharmacognosy; farmakognosi;

    Sammanfattning : The ocular hypotensive effect of topically applied prostaglandins is usually accompanied byconjunctival hyperaemia and irritation. The purpose of the present study was to investigate thepharmacological mechanism of the ocular surface hyperaemia induced by topically appliedprostaglandins, particularly prostaglandin F2α (PGF2α) and its synthetic analogue latanoprost, aselective FP prostanoid receptor agonist. LÄS MER

  3. 22. Procedural and postoperative pain-reducing methods in newborns

    Författare :Björn A Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Analgesia; anaesthesia; topical; local; epidural; lidocame; prilocaine; bupivacame; venepuncture; heel-lancing; skin thickness; skin perfusion; infant; neonate;

    Sammanfattning : The neonate has a functioning nociceptive system. However, neonates are probably more vulnerable than the older infants and adults to the negative effects of pain. Untreated pain and stress stimuli may have long-term effects. It is, therefore, very important to find ways to reduce pain and painful stimuli in neonates. LÄS MER

  4. 23. Non-invasive monitoring of low molecular weight biomarkers relevant to skin inflammation and cancer

    Författare :Skaidre Jankovskaja; Tautgirdas Ruzgas; Johan Engblom; György Marko-Varga; Melinda Rezeli; Pawel Lukasz Urban; Malmö universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tryptophan; Kynurenine; Phenylalanine; Tyrosine; Low molecular Weight Biomarkers; Non-Invasive; Skin Surface Sampling; Skin Permeability; Hydrogels; Prussian White; Health and society; Hälsa och samhälle;

    Sammanfattning : Development of skin inflammation and cancer in viable epidermis and dermis involve slow molecular weight (LMW) metabolites. We hypothesize that these LMW compounds can be collected on the surface of the skin and used for non-invasive diagnostics of skin disorders. LÄS MER

  5. 24. Biophysical aspects of the skin barrier : towards increased non-invasive extraction and optimized biomarker sampling

    Författare :Maxim Morin; Johan Engblom; Sebastian Björklund; Nicole K Brogden; Malmö universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The skin provides a link to the body’s health via its rich variety of high and low molecular weight biomarkers, reflecting both systemic diseases (e.g., cancer, diabetes) and local skin disorders (e.g. LÄS MER

  7. 25. Symptoms and aspects on eosinophil activity in allergic rhinitis

    Författare :Cecilia Ahlström-Emanuelsson; Lund näs- och halssjukdomar Öron-; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Allergic rhinitis is a major atopic disease. Even if much is known about the pathophysiology of this condition, and despite the fact that good treatments are available, there is a need for new treatment options, particularly for such aiming at new targets and reduced side effects. LÄS MER