Sökning: "Alzheimer’s disease AD"

Visar resultat 21 - 25 av 334 avhandlingar innehållade orden Alzheimer’s disease AD.

  1. 21. Neurodegenerative Biomarkers in Healthy Elderly - with special reference to the preclinical pattern of biological and cognitive markers for Alzheimer’s disease

    Författare :Erik Stomrud; Klinisk minnesforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cerebral blood flow; EEG; phosphorylated tau protein; amyloid beta protein; tau protein; cerebrospinal fluid; biomarkers; preclinical Alzheimer s disease; Alzheimer s disease; MCI; dementia; SPECT; memory; cognition; early diagnosis; control groups;

    Sammanfattning : Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by tau and amyloid brain pathology. With the gradual degeneration of neurons, cognitive symptoms will arise and the affected individual will eventually develop AD dementia. LÄS MER

  3. 22. Long Term Outcome and Prediction Models of Cognition, Activities of Daily Living and Nursing Home Placement in Alzheimer’s Disease with Cholinesterase Inhibitor Treatment

    Författare :Carina Wattmo; Klinisk minnesforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; longitudinal studies; nursing home placement; activities of daily living; cognition; Alzheimer s disease; cholinesterase inhibitors; disease progression; predictors; statistical models.;

    Sammanfattning : Background Prospective longitudinal studies in Alzheimer's disease (AD) that include cholinesterase inhibitor (ChEI) treatment in routine clinical settings are scarce. The patients vary in severity of the disease, clinical course, rate of progression and response to treatment. LÄS MER

  4. 23. The matter of white matter in Alzheimer's disease. -On white matter disease from neuropathology and neuroimaging to clinical presentation

    Författare :Martin Sjöbeck; Lund Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; medicinsk instrumentering; tomografi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; executive dysfunction; Clinical physics; magnetic resonance imaging; diffusion tensor imaging; neuropathology; microvascular pathology; astrocytes; myelin; oligodendrocytes; white matter disease; Alzheimer s disease; neuropsychology; neuropsykologi; Neurologi; neurophysiology; neurofysiologi; Psychiatry; clinical psychology; psychosomatics; Psykiatri; klinisk psykologi; psykosomatik; Neurology;

    Sammanfattning : Alzheimer's disease (AD) is the most prevalent type of dementing disorder. The cortical pathology of AD has been recognized for almost a century. In later years, an associated pathological feature of AD has been identified which affects the white matter. LÄS MER

  5. 24. The limbic-hypothalamic-pituitary-adrenal axis in Alzheimer's disease

    Författare :Birgitta Näsman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; multi-infarct dementia; hippocampus; temporal lobe; adrenal androgens; adrenocorticotropin; corticotropinreleasing hormone; cortisol; skin blanching;

    Sammanfattning : Dysfunction of the limbic-hypothalamic-pituitary-adrenal (LHPA) axis is a common finding in advanced dementia. In this study, the function of the LHPA axis at different levels was investigated in patients with dementia and in healthy elderly.A subtle disturbance in the feedback regulation of the LHPA axis was found in patients with early (i.e. LÄS MER

  7. 25. Alzheimer's Disease: The role of alpha1-antichymotrypsin-amyloid peptide (Abeta 1-42) interaction in the pathogenesis of Alzheimer's disease

    Författare :Yongxin Sun; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsykologi; neurophysiology; Neurologi; neuropsychology; Neurology; lipid metabolism.; inflammation; á1-antichymotrypsin; Alzheimer’s disease; amyloid-â peptide;

    Sammanfattning : Alzheimer?s disease (AD) is an age-related, irreversible brain disorder that occurs gradually and results in memory loss, behavioural and personality changes. The disease is characterized by an abnormal accumulation of amyloid-beta (Ab) peptide in the extracellular space and the protein Tau within nerve cells of certain regions of the brain. LÄS MER