Sökning: "biomarkers"

Visar resultat 1 - 5 av 983 avhandlingar innehållade ordet biomarkers.

  1. 1. Analysis of Metabolites in Complex Biological Samples Using LC/MS and Multivariate Data Analysis : Metabolic Fingerprinting and Detection of Biomarkers

    Författare :Helena Idborg; Sven Jacobsson; Per-Olof Edlund; Jonas Bergquist; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Metabolomics; Metabonomics; Metabolic Fingerprinting; Drug Metabolism; Biomarkers; Human Plasma; Rat Urine; LC MS; ZIC-HILIC; UPLC; UHPLC; ToF; Curve Resolution; Peak Detection; Pattern Recognition; Classification; PCA; PLS; PARAFAC; N-PLS; Data Fusion; Hierarchical Modeling; Batch modeling; Data Concatenation; Breast Cancer; Phospholipidosis; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : To facilitate early diagnosis of diseases and elucidation of the processes involved in their development and progression, various specific compounds or ‘biomarkers’ are often monitored. The first step is to decide which compounds to analyze. LÄS MER

  3. 2. Acute Pancreatitis. Biomarkers and radiology assessment

    Författare :Hanna Sternby; Kirurgi; []
    Nyckelord :acute pancreatitis; severity grade; Biomarkers; morphology; classification; radiology assessment; Acute pancreatitis; severity grade; Biomarkers; morphology; classification; radiology assessment;

    Sammanfattning : Background: Acute pancreatitis (AP) is a common and potentially severe disease. Early identification of severity grade is crucial for the outcome of the patient. For study approaches and comparison of inter-institutional data the AP patients need to be uniformly classified. LÄS MER

  4. 3. Joint disease biomarkers - discovery and application

    Författare :Dovilė Sinkevičiūtė; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; Osteoarthritis; Psoriatic arthritis; cartilage; Proteomics; Biomarkers; ELISA; Tissue culture; Extracellular matrix ECM ;

    Sammanfattning : Dysregulated cartilage homeostasis, articular cartilage degradation and abnormal bone remodeling are common denominators in joint disease and can lead to severe disability for the patients. The molecular pathways behind the disease pathology can overlap across different joint diseases. LÄS MER

  5. 4. Biomarkers and risk of intracerebral hemorrhage : population-based studies in northern Sweden

    Författare :Kristina Johansson; Marcus Lind; Lars Johansson; Jan-Håkan Jansson; Arne Lindgren; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intracerebral hemorrhage; hemorrhagic stroke; factor XII; D-dimer; von Willebrand factor; ABO blood groups; phosphatidylethanol; alcohol; risk markers; biomarkers; Medicine; medicin;

    Sammanfattning : BackgroundIntracerebral hemorrhage (ICH) is a disease associated with a high morbidity and mortality and treatment options for the condition are limited. Even though an ICH event usually comes as a surprise to the affected individual, pathogenetic processes often have occurred before the sudden ICH event and may have preceded disease onset by years. LÄS MER

  7. 5. Polyurethane - occupational exposure, biomarkers and symptoms

    Författare :Margareta Littorin; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spray; polyurethane; nose; metabolites; lung function ; lower airways; inflammation; heat; glue; genetic polymorphism; di isocyanate; Antibodies; biomarkers; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin; symptoms;

    Sammanfattning : Isocyanates may cause occupational asthma, rhinitis, and hypersensitivity pneumonitis. However, the mechanisms behind initiation of the disorders and the relations between exposure and effect are insufficiently elucidated. Means to biomonitor exposure and risk would be valuable. LÄS MER