Sökning: "hippocampus"

Visar resultat 1 - 5 av 383 avhandlingar innehållade ordet hippocampus.

  1. 1. The Influence of APOE ε4 on the Hippocampus and Hippocampus-Dependent Memory

    Författare :Eva Stening; Hedvig Söderlund; Clare Mackay; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; APOE ε4; episodic memory; spatial memory; hippocampus;

    Sammanfattning : APOE ε4 is the major genetic risk factor for Alzheimer’s disease, a dementia characterized by memory impairment and hippocampal atrophy. While associated with episodic impairment and reduced hippocampal volume in healthy aging, APOE ε4 has been related to increased episodic memory performance in young adults. LÄS MER

  3. 2. Making Head or Tail of the Hippocampus : A Long-Axis Account of Episodic and Spatial Memory

    Författare :Jonas Persson; Hedvig Söderlund; Tomas Furmark; Asaf Gilboa; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hippocampus; fMRI; episodic memory; spatial memory; gender differences; Psychology; Psykologi;

    Sammanfattning : While episodic and spatial memory both depend on the hippocampus, opposite gender differences in these functions suggest they are partly separate, with different neural underpinnings. The anterior and posterior hippocampus differ  in structure and whole-brain connectivity, and studies point to the posterior hippocampus being more involved in spatial memory while the anterior hippocampus’ role in episodic memory is less clear. LÄS MER

  4. 3. Genes to remember : imaging genetics of hippocampus-based memory functions

    Författare :Karolina Kauppi; Lars Nyberg; Jonas Persson; Guillén Fernández; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Imaging genetics; fMRI; Episodic memory; SNP; KIBRA; BDNF; APOE; Hippocampus; Parahippocampus;

    Sammanfattning : In the field of imaging genetics, brain function and structure are used as intermediate phenotypes between genes and cognition/diseases to validate and extend findings from behavioral genetics. In this thesis, three of the strongest candidate genes for episodic memory, KIBRA, BDNF, and APOE, were examined in relation to memory performance and hippocampal/parahippocampal fMRI blood-oxygen level-dependent (BOLD) signal. LÄS MER

  5. 4. Plasticity of the developing glutamate synapse in the hippocampus

    Författare :Therése Abrahamsson; Göteborgs universitet; []
    Nyckelord :synaptic plasticity; long-term potentiation; short-term potentiation; silent synapse; development; hippocampus; glutamate;

    Sammanfattning : Synapses are highly plastic, i.e. they have the ability to change their signaling strength both in the short- and long-term (e.g. LÄS MER

  7. 5. Characterizing and modulating the effects of ionizing radiation to the juvenile hippocampus

    Författare :Malin Blomstrand; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; low-dose radiation; CNS; hippocampus; apoptosis; cytokines; growth factors; microglia; medulloblastoma; hippocampal sparing; tumor bed boost; cognitive risk estimation;

    Sammanfattning : Survival rates after childhood cancer treatment have improved, leading to a growing population of survivors. Radiotherapy is an important tool for curing cancer in the brain. Unfortunately, radiotherapy is associated with late side effects e.g. LÄS MER