Visar resultat 1 - 5 av 353 avhandlingar innehållade ordet hippocampus.
Sammanfattning : APOE ε4 is the major genetic risk factor for Alzheimer’s disease, a dementia characterized by memory impairment and hippocampal atrophy. While associated with episodic impairment and reduced hippocampal volume in healthy aging, APOE ε4 has been related to increased episodic memory performance in young adults. LÄS MER
Sammanfattning : While episodic and spatial memory both depend on the hippocampus, opposite gender differences in these functions suggest they are partly separate, with different neural underpinnings. The anterior and posterior hippocampus differ in structure and whole-brain connectivity, and studies point to the posterior hippocampus being more involved in spatial memory while the anterior hippocampus’ role in episodic memory is less clear. LÄS MER
Sammanfattning : In the field of imaging genetics, brain function and structure are used as intermediate phenotypes between genes and cognition/diseases to validate and extend findings from behavioral genetics. In this thesis, three of the strongest candidate genes for episodic memory, KIBRA, BDNF, and APOE, were examined in relation to memory performance and hippocampal/parahippocampal fMRI blood-oxygen level-dependent (BOLD) signal. LÄS MER
Sammanfattning : Synapses are highly plastic, i.e. they have the ability to change their signaling strength both in the short- and long-term (e.g. LÄS MER
Sammanfattning : Survival rates after childhood cancer treatment have improved, leading to a growing population of survivors. Radiotherapy is an important tool for curing cancer in the brain. Unfortunately, radiotherapy is associated with late side effects e.g. LÄS MER