Sökning: "renal development"

Visar resultat 1 - 5 av 205 avhandlingar innehållade orden renal development.

  1. 1. The renin-angiotensin system in renal tubulogenesis. Experimental studies in the rat

    Författare :Daina Lasaitiene; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :angiotensin II; extracellular matrix; inflammation; mitochondrial biogenesis; renal development; renin-angiotensin system; thick ascending limb of Henle; tubulogenesis;

    Sammanfattning : The kidney and the renin-angiotensin system (RAS) are vital regulators of blood pressure and salt-water balance. In order to appropriately regulate circulatory homeostasis, the kidney must undergo normal development, in which the RAS plays a crucial role. LÄS MER

  2. 2. Renal function after transplantation of the liver and intestine

    Författare :Gustaf Herlenius; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :adult liver transplantation; pediatric liver transplantation; intestinal transplantation; multivisceral transplantation; immunosuppression; calcineurin inhibitors; glomerular filtration rate; renal function; nephrotoxicity; chronic kidney disease; renal replacement therapy; mortality;

    Sammanfattning : Background: Chronic kidney disease (CKD) after liver (LT) or intestinal (IT) transplantation may decrease patient survival. Calcineurin inhibitors (CNI) play a major role in its development. Aims: Describe long term renal function and risk factors for developing CKD in adults and children after LT and IT. LÄS MER

  3. 3. Molecular genetic aspects of renal cell carcinoma development

    Författare :Andrei Alimov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Kidney tumor; RCC; LOH; CGH; SKY; PTEN; chromosome 3p; chromosome 10q; chromosome 14q;

    Sammanfattning : Renal cell carcinoma (RCC) is the most common tumor of the renal parenchyma. The aim of this study was to further characterize known as well as new genetic abnormalities in a clinical material of RCC, as well as in established cell lines to gain more information about etiological and progression factors. LÄS MER

  4. 4. Development of Salt-Sensitive Hypertension in Hydronephrosis

    Författare :Mattias Carlström; Erik Persson; Nils Wåhlin; Russell Brown; Göran Bergström; Uppsala universitet; []
    Nyckelord :Physiology; blood pressure; nephrectomy; nitric oxide; oxidative stress; renal function; renin angiotensin system; salt-sensitivity; telemetry; tubuloglomerular feedback; ureteral obstruction; Fysiologi;

    Sammanfattning : Hydronephrosis, due to ureteropelvic junction obstruction, is a common condition in infants with an incidence of approximately 0.5-1%. During the last decade, the surgical management of non-symptomatic hydronephrosis has become more conservative, and the long-term physiological consequences of this new policy are unclear. LÄS MER

  5. 5. End stage renal disease in type 1 diabetes : time trends and risk factors

    Författare :Cecilia Toppe; Anna Möllsten; Gisela Dahlquist; Torild Skrivarhaug; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; End stage renal disease; renal replacement therapy; type 1 diabetes; diabetes nephropathy; socioeconomy and epidemiology; epidemiologi; Epidemiology; pediatrik; Pediatrics;

    Sammanfattning : Background and aims: Sweden has a high incidence of type 1 diabetes (T1D) and the incidence is increasing worldwide. The incidence is now twice as high as when the registration of childhood onset T1D in Sweden started in 1977. One of the major risk factors for developing late complications such as renal failure (ESRD) is duration of T1D. LÄS MER