Sökning: "renal development"

Visar resultat 1 - 5 av 221 avhandlingar innehållade orden renal development.

  1. 1. The renin-angiotensin system in renal tubulogenesis. Experimental studies in the rat

    Författare :Daina Lasaitiene; Göteborgs universitet; []
    Nyckelord :angiotensin II; extracellular matrix; inflammation; mitochondrial biogenesis; renal development; renin-angiotensin system; thick ascending limb of Henle; tubulogenesis;

    Sammanfattning : The kidney and the renin-angiotensin system (RAS) are vital regulators of blood pressure and salt-water balance. In order to appropriately regulate circulatory homeostasis, the kidney must undergo normal development, in which the RAS plays a crucial role. LÄS MER

  3. 2. Renal function after transplantation of the liver and intestine

    Författare :Gustaf Herlenius; Göteborgs universitet; []
    Nyckelord :adult liver transplantation; pediatric liver transplantation; intestinal transplantation; multivisceral transplantation; immunosuppression; calcineurin inhibitors; glomerular filtration rate; renal function; nephrotoxicity; chronic kidney disease; renal replacement therapy; mortality;

    Sammanfattning : Background: Chronic kidney disease (CKD) after liver (LT) or intestinal (IT) transplantation may decrease patient survival. Calcineurin inhibitors (CNI) play a major role in its development. Aims: Describe long term renal function and risk factors for developing CKD in adults and children after LT and IT. LÄS MER

  4. 3. Molecular genetic aspects of renal cell carcinoma development

    Författare :Andrei Alimov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Kidney tumor; RCC; LOH; CGH; SKY; PTEN; chromosome 3p; chromosome 10q; chromosome 14q;

    Sammanfattning : Renal cell carcinoma (RCC) is the most common tumor of the renal parenchyma. The aim of this study was to further characterize known as well as new genetic abnormalities in a clinical material of RCC, as well as in established cell lines to gain more information about etiological and progression factors. LÄS MER

  5. 4. Development of Salt-Sensitive Hypertension in Hydronephrosis

    Författare :Mattias Carlström; Erik Persson; Nils Wåhlin; Russell Brown; Göran Bergström; Uppsala universitet; []
    Nyckelord :Physiology; blood pressure; nephrectomy; nitric oxide; oxidative stress; renal function; renin angiotensin system; salt-sensitivity; telemetry; tubuloglomerular feedback; ureteral obstruction; Fysiologi;

    Sammanfattning : Hydronephrosis, due to ureteropelvic junction obstruction, is a common condition in infants with an incidence of approximately 0.5-1%. During the last decade, the surgical management of non-symptomatic hydronephrosis has become more conservative, and the long-term physiological consequences of this new policy are unclear. LÄS MER

  7. 5. Aspects of renal blood flow and oxygenation in acute kidney injury during severe infections

    Författare :Tomas Luther; Robert Frithiof; Michael Hultström; Per Liss; Rafael Kawati; Anders Åneman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute kidney injury; renal blood flow; renal oxygenation; COVID-19; fluids; mitochondria; sepsis; acute respiratory distress syndrome; magnetic resonance imaging; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : Acute kidney injury (AKI) is a common complication in patients treated in the intensive care unit (ICU). Severe infections/sepsis is the most common aetiology, and about half of patients treated in the ICU due to sepsis are affected. Although AKI often resolves over time, the development of AKI decreases the chances of surviving. LÄS MER