Sökning: "renal development"

Visar resultat 21 - 25 av 221 avhandlingar innehållade orden renal development.

1. 21. Molecular mechanisms of tumor development in hyperparathyroidism

   Författare :Filip Farnebo; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :parathyroid; hyperparathyroidism; MEN 1; FIHP; loss of heterozygosity; comparative genomic hybridization; mutation analysis; in situ hybridization;

   Sammanfattning : Loss of heterozygosity (LOH) analysis and comparative genomic hybridization (CGH) were used in an attempt to identify recurrent chromosomal alterations in different types of parathyroid tumors. These included familial and sporadic, benign and malignant, as well as primary, irradiation associated and secondary tumors. LÄS MER

3. 22. Molecular genetics of kidney cancer : chromosomal regions of importance in the development of renal cell carcinoma

   Författare :Rikard Erlandsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Carcinoma; renal cell Chromosomes; human; pair 3 Chromosome deletion Genes; suppressor; tumor Sequence analysis; DNA. Renal cell carcinoma RCC is a malignancy of the human kidney; occurring most commonlyduring the seventh and eighth decades of;

   Sammanfattning : Renal cell carcinoma (RCC) is a malignancy of the human kidney, occurring most commonly during the seventh and eighth decades of life. The incidence is high in the Nordic countries and the five year survival is 40-50%. Smoking is a risk factor inferring a minor increase in risk. The best established risk factor is obesity. LÄS MER

4. 23. Diabetes-induced Alterations in Renal Microcirculation and Metabolism

   Författare :Fredrik Palm; Per Liss; Peter Hansell; Per-Ola Carlsson; Gerald DiBona; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; diabetes mellitus; kidney; nephropathy; oxygen tension; haemodynamic; nitric oxide; oxygen consumption; radical oxygen species; polyol pathway; Fysiologi; Physiology; Fysiologi;

   Sammanfattning : Diabetes-induced renal complications, i.e. diabetes nephropathy, are a major cause of morbidity and mortality. The exact mechanism mediating the negative influence of hyperglycaemia on renal function is unclear, although several hypotheses have been postulated. LÄS MER

5. 24. Studies on renal progenitor cells and kidney cancer

   Författare :Jennifer Hansson; Avdelningen för translationell cancerforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Kidney cancer and renal injuries affect millions of people in the world resulting in high patient morbidity and mortality, as well as one of the most extensive medical costs for society. Upon renal injury the kidney has an endogenous ability to repair damaged tubules and restore kidney function, provided that the patient receives adequate supportive care in time. LÄS MER

7. 25. DNA methylation as a prognostic marker in clear cell Renal Cell Carcinoma

   Författare :Emma Andersson-Evelönn; Sofie Degerman; Magnus Hultdin; Göran Roos; Börje Ljungberg; Ralph Peeker; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clear cell renal cell carcinoma; DNA methylation; Prognosis; Clinical outcome; Epigenetic classifiers;

   Sammanfattning : Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cell carcinoma worldwide. Metastatic ccRCC is correlated to poor prognosis whereas non-metastatic disease has a 5-year survival rate up to 90%. LÄS MER