Sökning: "c-jun"

Visar resultat 1 - 5 av 69 avhandlingar innehållade ordet c-jun.

  1. 1. JNK/c-Jun Signaling and Peripheral Nerve Regeneration

    Detta är en avhandling från Lund University, Dept. of Cell and Organism Biology

    Författare :Charlotta Lindwall; [2005]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neuropsykologi; neurofysiologi; neurophysiology; Neurologi; neuropsychology; Neurology; Djurfysiologi; Animal physiology; JNK; signal transduction; nerve regeneration;

    Sammanfattning : The events associated with axonal injury in the peripheral nervous system (PNS) have been described in detail. However, the molecular mechanisms underlying the regenerative response, or neuronal cell death, following axonal injury are poorly understood. LÄS MER

  2. 2. Studies on two transcription regulatory proteins : cellular C-jun and adenovirus E1A

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Kerstin Sollerbrant; Karolinska Institutet.; Karolinska Institutet.; [1996]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adenovirus; EIA; EIB; transcription; CtBP; c-Jun; Gal4;

    Sammanfattning : STUDIES ON TWO TRANSCRIPTION REGULATORY PROTEINS: CELLULAR C-JUN AND ADENOVIRUS ElA. KERSTIN SOLLERBRANT Departrnent of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, S-171 77 Stockholm, Sweden. Adenoviruses cause Iytic infections in a range of mammalian cells, but can in certain cases also transform the host cell. LÄS MER

  3. 3. Cellular mechanisms of taxane therapy in castration resistant prostate cancer

    Detta är en avhandling från Division of urological research

    Författare :Martina Tinzl; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; chemotherapy; taxane; c-jun; androgen receptor; PSA;

    Sammanfattning : Chemotherapy of castration resistant prostate cancer (CRPC) is based on taxane formulations worldwide. Only 30-50 % of patients respond to this therapy and the exact cellular mechanisms of taxane resistance in PC cells are not fully elucidated. There is convincing evidence that androgen receptor (AR) is affected by exposure to these compounds. LÄS MER

  4. 4. Effects of ethanol on the expression of immediate-early genes in nerve cells

    Detta är en avhandling från Division of urological research

    Författare :Wei-Qun Ding; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroadaptation; the central nervous system; AP-1; junD; junB; c-jun; fosB; c-fos; neuroblastoma SH-SY5Y; ethanol; immediate-early genes; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Immediate-early genes of the fos and jun families encode proteins that dimerize to form a complex of activator protein 1 and regulate the expression of a number of genes in the nervous system. Ethanol has previously been shown to induce alterations in expression of fos and jun genes in the brain. LÄS MER

  5. 5. TRAF6 stimulates TGFβ-induced oncogenic signal transduction in cancer cells

    Detta är en avhandling från Division of urological research

    Författare :Shyam Kumar Gudey; Marene Landström; Urban Lendahl; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; c-Jun; invasion; non-Smad; Notch; NICD; oncogenesis; presenilin1; PKCζ; prostate cancer; p21; p38; p300; Snail1; TGFβ; TβRI; TACE; TRAF6; ubiquitination; TGFbeta signal transduction; patologi; Pathology;

    Sammanfattning : Prostate cancer is one of the leading causes of cancer-related deaths in men worldwide, with 10,000 new cases/year diagnosed in Sweden. In this context, there is an urgent need to identify new biomarkers to detect prostate cancer at an initial stage for earlier treatment intervention. LÄS MER