Sökning: "renal development"

Visar resultat 6 - 10 av 221 avhandlingar innehållade orden renal development.

  1. 6. End stage renal disease in type 1 diabetes : time trends and risk factors

    Författare :Cecilia Toppe; Anna Möllsten; Gisela Dahlquist; Torild Skrivarhaug; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; End stage renal disease; renal replacement therapy; type 1 diabetes; diabetes nephropathy; socioeconomy and epidemiology; epidemiologi; Epidemiology; pediatrik; Pediatrics;

    Sammanfattning : Background and aims: Sweden has a high incidence of type 1 diabetes (T1D) and the incidence is increasing worldwide. The incidence is now twice as high as when the registration of childhood onset T1D in Sweden started in 1977. One of the major risk factors for developing late complications such as renal failure (ESRD) is duration of T1D. LÄS MER

  3. 7. Localised and Metastatic Renal Cell Carcinoma. Aspects of Treatment

    Författare :David Lyrdal; Göteborgs universitet; []
    Nyckelord :renal cell carcinoma; nephron-sparing surgery; 18F -2-flouro-2-deoxyglucose; positron emission tomography; metastatic renal cell carcinoma; peg-interferon alfa-2b; radiofrequency; ablation; percutaneous; ultrasound;

    Sammanfattning : Localised and Metastatic Renal Cell Carcinoma. Aspects of Treatment. Aims: Paper I To assess the long-term results in patients operated with NSS in situ for RCC, with special reference to their dependence on tumour grade and stage. LÄS MER

  4. 8. Renal injury in liver transplantation clinical and mechanistic studies

    Författare :Åsa Norén; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver transplantation; Renal injury; Ischemia reperfusion injury;

    Sammanfattning : ABSTRACT Background: Renal injury in liver transplantation (LT) is common and presents both as early and late insufficiency. These conditions are interconnected and have substantial impact on the long-term outcome. LÄS MER

  5. 9. Safety and Efficacy Modelling in Anti-Diabetic Drug Development

    Författare :Bengt Hamrén; Mats O Karlsson; Eric Snoeck; Uppsala universitet; []
    Nyckelord :Pharmaceutical biosciences; pharmacokinetic; pharmacodynamic; mechanism-based; modelling; type 2 diabetes mellitus; tesaglitazar; PPAR; drug development; NONMEM; Farmaceutisk biovetenskap;

    Sammanfattning : A central aim in drug development is to ensure that the new drug is efficacious and safe in the intended patient population. Mathematical models describing the pharmacokinetic-pharmacodynamic (PK-PD) properties of a drug are valuable to increase the knowledge about drug effects and disease and can be used to inform decisions. LÄS MER

  7. 10. Children with symptomatic urinary tract infection in Göteborg 1970-79 followed for two decades

    Författare :Martin Wennerström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urinary tract infection; vesicoureteral reflux; renal scarring; children; adults; renal function; hypertension; ambulatory blood pressure; atrial natriuretic peptide;

    Sammanfattning : Objective: To study a populationbased cohort of subjects, detected after their first known urinary tract infection (UTI) with special focus on: the natural course of vesicoureteral reflux; the prevalence of renal scarring, age at detection and factors of importance for its development; the long term risk of impaired renal function and hypertension. Methods: Analyses of data, prospectively registered during childhood, and an adulthood follow-up investigation evaluating renal function by 51Cr-EDTA clearance and blood pressure by 24-hour ambulatory technique. LÄS MER