Sökning: "tubulogenesis"

Visar resultat 1 - 5 av 8 avhandlingar innehållade ordet tubulogenesis.

  1. 1. The renin-angiotensin system in renal tubulogenesis. Experimental studies in the rat

    Författare :Daina Lasaitiene; Göteborgs universitet; []
    Nyckelord :angiotensin II; extracellular matrix; inflammation; mitochondrial biogenesis; renal development; renin-angiotensin system; thick ascending limb of Henle; tubulogenesis;

    Sammanfattning : The kidney and the renin-angiotensin system (RAS) are vital regulators of blood pressure and salt-water balance. In order to appropriately regulate circulatory homeostasis, the kidney must undergo normal development, in which the RAS plays a crucial role. LÄS MER

  3. 2. Embryonic ecdysone-induced gene expression and progression of organ morphogenesis

    Författare :Tina Mitra Chavoshi Alizadeh; Göteborgs universitet; []
    Nyckelord :Drosophila; trachea; hindgut; tubulogenesis; luminal matrix; ecdysteroid; EcR:Usp; dorsal closure;

    Sammanfattning : The formation of an epithelial organ requires a set of organ-specific gene programs that instruct parallel and successive developmental events. Still, it is unclear what are the core regulatory programs and how such programs are timely coordinated within the organ. LÄS MER

  4. 3. Rho-GTPases in Morphogenesis and Differentiation of the Developing Pancreas

    Författare :Thomas Greiner; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; insulin; diabetes; beta cell; cell adhesion; migration; delamination; morphogenesis; tubulogenesis; pancreas; Cdc42; Rho-GTPase; Rac1;

    Sammanfattning : Branched tubular networks constitute the basic structure of many organs to increase surface area and to transport fluids and gases. Glandular organs such as the pancreas arise from multilayered epithelium, which undergoes de novo lumen formation and extensive remodeling and branching. LÄS MER

  5. 4. ENDOTHELIAL- EPITHELIAL INTERACTIONS Blood vessels friends or foes?

    Författare :Fredrik Wolfhagen Sand; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; blood vessels; pancreas; endoderm development; S1P1; N-CAM; diabetic retinopathy; diabetes; tubulogenesis; Cdc42;

    Sammanfattning : Diabetes affects enormous amounts of patients. In type 1 diabetes the insulin producing β cells in the islet of Langerhans are destroyed by the immune system. The β cells, which are located in the pancreas, regulate blood glucose levels. The lack of insulin production requires administration of insulin. LÄS MER

  7. 5. Genetic dissection of tubulogenesis in the Drosophila trachea

    Författare :Johanna Hemphälä; Christos Samakovlis; Reinhard Schuh; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; trachea; transposon mutagenesis screen; fusion; Dpp; Delta; tubular dimensions; Grainyhead; Krotzkopf verkehrt; intralumenal matrix; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : The formation of branched tubular organs, such as the mammalian lung kidney and vascular system, is an essential process in animal development. The Drosophila tracheal (respiratory) system provides a genetic model system to study the highly ordered process of branch outgrowth and fusion required to form continuous tubular networks. LÄS MER