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Visar resultat 6 - 10 av 166 avhandlingar som matchar ovanstående sökkriterier.

1. 6. Internal Dosimetry Development and Evaluation of Methods and Models

   Författare :Lena M Jönsson; Lund Medicinsk strålningsfysik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; Klinisk fysiologi; medical instrumentation; tomography; radiology; Clinical physics; crypt cells; intestine; radionuclide; scintillation camera; sestamibi; activity quantification; conjugate view method; Monte Carlo simulation; internal dosimetry; Nuclear medicine; radiobiology; Nukleärmedicin; radiobiologi; medicinsk instrumentering; radiologi;

   Sammanfattning : Radionuclide therapy requires patient-specific planning of the absorbed dose to target volumes, in most cases tumours, in order to achieve an expected biological effect, taking into account that the absorbed doses to normal organs and tissues should be kept as low as reasonably achievable. Therefore, the calculation of absorbed doses has to be as accurate as possible. LÄS MER

3. 7. Radionuclides in the Baltic Sea : Ecosystem models and experiments on transport and fate

   Författare :Linda Kumblad; Nils Kautsky; Ulrik Kautsky; Michael Gilek; Michael Thorne; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; radionuclide; baltic sea; ecosystem model; ecosystem dynamics; risk assessment; safety assessment; benthic invertebrates; bioturbation; bioaccumulation; remobilisation; Terrestrial; freshwater and marine ecology; Terrestisk; limnisk och marin ekologi;

   Sammanfattning : Manmade radionuclides have been introduced to the environment for almost a century. The main source has been the nuclear weapons testing programmes, but accidental releases from the nuclear power production industries have also contributed. The risk to humans from potential releases from nuclear facilities is evaluated in safety assessments. LÄS MER

4. 8. RADIOIMMUNOTHERAPY & EXTRACORPOREAL ADSORPTION Preclinical Studies of the Pharmacokinetics & Biotinylation of Radioimmunoconjugates in Immunocompetent Rats

   Författare :Zhongmin Wang; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; cancer; oncology; cancerology; Cytologi; Cytology; extracorporeal adsorption; tri-functional chelator; maximal tolerable dose; biotin; intraperitoneal administration; biodistribution; pharmacokinetics; biotinylation; radiolabeling; rat; monoclonal antibody; radionuclide;

   Sammanfattning : Extracorporeal adsorption (ECAT) is a novel strategy to reduce activity in whole body (WB), blood and radiosensitive organs by removing the excess of radiolabeled and biotinylated monoclonal antibody (MAb) from blood so that tumor/normal tissue ratio (T/N) could be improved. By increasing T/N, higher amounts of radiolabeled MAb might be administered, making it possible to treat disseminated carcinomas. LÄS MER

5. 9. Targeted Therapy of Colorectal Cancer : Preclinical Evaluation of a Radiolabelled Antibody

   Författare :Ylva Almqvist; Anders Sundin; Vladimir Tolmachev; Hans Lundqvist; Matthew K Robinson; Uppsala universitet; []
   Nyckelord :Molecular medicine; tumour targeting; antibody; A33; radionuclide; colorectal cancer; therapy; Molekylärmedicin;

   Sammanfattning : Targeted radiotherapy (TRT) of cancer is a promising approach that enables selective treatment of tumour cells, while sparing normal tissue. The humanized monoclonal antibody A33 (huA33) is a potential targeting agent for TRT of colorectal cancer, since its antigen is expressed in more than 95 % of all colorectal carcinomas. LÄS MER

7. 10. On Weapons Plutonium in the Arctic Environment (Thule, Greenland)

   Författare :Mats Eriksson; Lund Medicinsk strålningsfysik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear physics; Kärnfysik; Nuclear medicine; radiobiology; Nukleärmedicin; radiobiologi; Nuclear engineering and technology; Kärnteknik; realtime digital image systems; SEM; ICP-MS; alpha spectrometry; gamma spectrometry; heterogeneous activity concentration; hot particle; separation technique; isotopic ratio; inventory; source term; fallout; americium; uranium; plutonium; radionuclide; Bylot Sound; Greenland; Thule; environmental radioactivity; nuclear accident;

   Sammanfattning : This thesis concerns a nuclear accident that occurred in the Thule (Pituffik) area, NW Greenland in 1968, called the Thule accident. Results are based on different analytical techniques, i.e. gamma spectrometry, alpha spectrometry, ICP-MS, SEM with EDX and different sediment models, i. LÄS MER