Sökning: "internal dosimetry"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden internal dosimetry.

  1. 1. Internal dosimetry. Macroscopic, small-scale and microscopic perspectives

    Detta är en avhandling från Cecilia Hindorf, Dept. of Medical Radiation Physics, Lund University Hospital, SE-221 85 Lund, Sweden

    Författare :Cecilia Hindorf; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiobiologi; Nukleärmedicin; radiobiology; Nuclear medicine; B-cell lymphoma; Radioimmunotherapy; Radionuclide therapy; Internal dosimetry; Radiopharmaceutical technology; Radiofarmaceutisk teknik;

    Sammanfattning : Internal dosimetry deals with the assessment of absorbed dose for radionuclides distributed inside the body. The absorbed dose is in its turn used for correlation with the biological effect caused by the irradiation. LÄS MER

  2. 2. Internal Dosimetry Development and Evaluation of Methods and Models

    Detta är en avhandling från Medical Radiation Physics, Lund University

    Författare :Lena M Jönsson; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; Klinisk fysiologi; medical instrumentation; tomography; radiology; Clinical physics; crypt cells; intestine; radionuclide; scintillation camera; sestamibi; activity quantification; conjugate view method; Monte Carlo simulation; internal dosimetry; Nuclear medicine; radiobiology; Nukleärmedicin; radiobiologi; medicinsk instrumentering; radiologi;

    Sammanfattning : Radionuclide therapy requires patient-specific planning of the absorbed dose to target volumes, in most cases tumours, in order to achieve an expected biological effect, taking into account that the absorbed doses to normal organs and tissues should be kept as low as reasonably achievable. Therefore, the calculation of absorbed doses has to be as accurate as possible. LÄS MER

  3. 3. Quantification Methods for Clinical Studies in Nuclear Medicine - Applications in AMS, PET/CT and SPECT/CT

    Detta är en avhandling från Lund University, dept. of Medical Radiation Physics

    Författare :Marie Sydoff; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nuclear Medicine; AMS; PET CT; SPECT CT; dosimetry; internal dosimetry; quantification; activity quantification; volume delineation; radiation; biokinetics; pharmacokinetics; biodistribution;

    Sammanfattning : An essential part of the development of new radiopharmaceuticals for use in diagnostic nuclear medicine is the determination of its biokinetic properties. The uptake and turn-over of the radiopharmaceutical in the source organs is of great interest since this could determine whether the radiopharmaceutical would be suitable for clinical use or not. LÄS MER

  4. 4. Realistic tissue dosimetry models using Monte Carlo simulations. Applications for radionuclide therapies

    Detta är en avhandling från Department of Medical Radiation Physics, Clinical Sciences, Lund, Lund University

    Författare :Erik Larsson; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; internal dosimetry; radionuclide therapy; Monte Carlo; small scale dosimetry;

    Sammanfattning : Radionuclide therapy (RNT) is a generic term for treatment modalities that use a radionuclide labeled to a target-specific molecule. This so-called radiopharmaceutical accumulates in the target, where the ionizing radiation damages the cells. At sufficient levels of radiation, the cells cannot repair themselves. LÄS MER

  5. 5. Small-Scale Absorbed Dose Modelling in Selective Internal Radiation Therapy Microsphere Distribution in Normal Liver Tissue

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Jonas Högberg; Göteborgs universitet.; Gothenburg University.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clusters; dosimetry; heterogeneity; liver; microspheres; radioembolisation; simulations; SIRT; surgery; yttrium-90;

    Sammanfattning : Radioembolisation (RE), with yttrium-90 (90Y) labelled microspheres, is an increasingly common treatment method for unresectable liver tumours. The tolerable mean absorbed dose for normal liver (NL) tissue is higher in RE than in External Beam Radiation Therapy (EBRT); absorbed dose heterogeneity is thought to be one important reason, together with a low absorbed dose rate, but the knowledge of microsphere distributions is limited. LÄS MER