Sökning: "patient selection"

Visar resultat 1 - 5 av 197 avhandlingar innehållade orden patient selection.

  1. 1. Statistical Feature Selection : With Applications in Life Science

    Författare :Roland Nilsson; Jesper Tegnér; Johan Björkegren; Sepp Hochreiter; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Machine learning; supervised learning; classification; dimemsionality reduction; multiple testing; gene expression; microarray; cancer; Bioinformatics; Bioinformatik;

    Sammanfattning : The sequencing of the human genome has changed life science research in many ways. Novel measurement technologies such as microarray expression analysis, genome-wide SNP typing and mass spectrometry are now producing experimental data of extremely high dimensions. LÄS MER

  2. 2. Covariate Model Building in Nonlinear Mixed Effects Models

    Författare :Jakob Ribbing; E. Niclas Johnsson; Mats O. Karlsson; Janet Wade; Uppsala universitet; []
    Nyckelord :Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Pharmacodynamics; Modeling; Covariate selection; Stepwise selection; Covariate analysis; Methodology; Model validation; Model evaluation; Type-2 diabetes; Beta-cell function; Meta analysis; Cross-validation; Least absolute shrinkage and selection operator; Pharmacometrics; ED optimization; Farmakokinetik Farmakoterapi;

    Sammanfattning : Population pharmacokinetic-pharmacodynamic (PK-PD) models can be fitted using nonlinear mixed effects modelling (NONMEM). This is an efficient way of learning about drugs and diseases from data collected in clinical trials. LÄS MER

  3. 3. Uvulopalatopharyngoplasty : patient selection, long- term outcomes, and side effects

    Författare :Joar Sundman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Uvulopalatopharyngoplasty (UPPP) is the most common surgical treatment for adult patients with obstructive sleep apnea (OSA). Its short-term efficacy, as measured through polysomnography, is well-established and has been demonstrated in two randomized controlled trials in recent years. LÄS MER

  4. 4. Surveys and services : The feasibility of conducting research in Swedish community pharmacies

    Författare :Pia Frisk; Sofia Kälvemark-Sporrong; Margareta Hammarlund-Udenaes; Björn Wettermark; Marcel L Bouvy; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; Community pharmacy; Pharmaceutical services; Drug utilization research; Survey; Patient; Pharmaceutical care; Feasibility; Sweden; Social Pharmacy; Samhällsfarmaci;

    Sammanfattning : For the past decades, there has been a shift in community pharmacy practice from dispensing and compounding towards provision of pharmacy services. Research is important to generate evidence for new services within pharmacy practice. LÄS MER

  5. 5. Radiation therapy of upper gastrointestinal cancers with scanned proton beams : A treatment planning study

    Författare :Gracinda Mondlane; Albert Siegbahn; Michael Gubanski; Iuliana Toma-Dasu; Crister Ceberg; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Treatment planning; gastric cancer; liver metastases; photon beam therapy; proton beam therapy; dosimetric comparison; normal tissue complication probability; risk of radiation-induced secondary cancer; patient selection; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : Proton beam therapy (PBT), using scanned beams, is an emerging modality used for the treatment of cancer. The clinical advantages of PBT, compared to commonly used photon beam therapy, have been demonstrated in different studies. LÄS MER