Sökning: "Bioinformatik"

Visar resultat 1 - 5 av 299 avhandlingar innehållade ordet Bioinformatik.

  1. 1. On protein structure, function and modularity from an evolutionary perspective

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Robert Pilstål; Linköpings universitet.; Linköpings universitet.; [2018]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; structure; biology; intrinsical; disorder; protein; sequence; evolution; mutation; epistasis; function; allostery; dynamics; simulation; prediction; graph; network; bioinformatik; struktur; biologi; strukturbiologi; intrinsiellt; oordnad; protein; sekvens; evolution; mutation; epistasis; funktion; allosteri; dynamik; simulation; prediktion; graf; nätverk;

    Sammanfattning : We are compounded entities, given life by a complex molecular machinery. When studying these molecules we have to make sense of a diverse set of dynamical nanostructures with wast and intricate patterns of interactions. LÄS MER

  2. 2. Bioinformatic Methods in Metagenomics

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Johannes Alneberg; KTH.; KTH.; [2018]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Bioinformatics; Metagenomics; Microbiome; Binning; Baltic Sea; Bioinformatik; Metagenomik; Mikrobiom; Binning; Östersjön;

    Sammanfattning : Microbial organisms are a vital part of our global ecosystem. Yet, our knowledge of them is still lacking. Direct sequencing of microbial communities, i.e. LÄS MER

  3. 3. Rule-based Models of Transcriptional Regulation and Complex Diseases Applications and Development

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Susanne Bornelöv; Uppsala universitet.; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Histone modification; Transcription factor; Transcriptional regulation; Next-generation sequencing; Feature selection; Machine learning; Rule-based classification; Asthma; Allergy; Bioinformatik; Bioinformatics;

    Sammanfattning : As we gain increased understanding of genetic disorders and gene regulation more focus has turned towards complex interactions. Combinations of genes or gene and environmental factors have been suggested to explain the missing heritability behind complex diseases. LÄS MER

  4. 4. The Nucleosome as a Signal Carrying Unit From Experimental Data to Combinatorial Models of Transcriptional Control

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Stefan Enroth; Uppsala universitet.; [2010]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Next generation sequencing; Nucleosome; Histone modification; Transcriptional regulation; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; TECHNOLOGY Bioengineering Bioinformatics; TEKNIKVETENSKAP Bioteknik Bioinformatik; Bioinformatik; Bioinformatics;

    Sammanfattning : The human genome consists of over 3 billion nucleotides and would be around 2 meters long if uncoiled and laid out. Each human somatic cell contains all this in their nucleus which is only around 5 µm across. This extreme compaction is largely achieved by wrapping the DNA around a histone octamer, the nucleosome. LÄS MER

  5. 5. Characterization of protein families, sequence patterns, and functional annotations in large data sets

    Detta är en avhandling från Institutionen för fysik, kemi och biologi

    Författare :Anders Bresell; Linköpings universitet.; Linköpings universitet.; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioinformatics; sequence analysis; patterns; protein families; NATURAL SCIENCES Chemistry Theoretical chemistry Bioinformatics; NATURVETENSKAP Kemi Teoretisk kemi Bioinformatik;

    Sammanfattning : Bioinformatics involves storing, analyzing and making predictions on massive amounts of protein and nucleotide sequence data. The thesis consists of six papers and is focused on proteins. LÄS MER