Sökning: "Drug utilization research"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden Drug utilization research.

1. 1. The influence of gender and depression on drug utilization : Pharmacoepidemiological research in Sweden

   Författare :Lena Thunander Sundbom; Göran Frenning; Kerstin Hedborg; Susanna Wallerstedt; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adherence; anxiety; depression; drug utilization; gender; pharmacoepidemiology; prescription drugs; self-report; Farmakoepidemiologi; Pharmacoepidemiology; Health-Promoting Work;

   Sammanfattning : Background Drug use has increased over recent decades, and is especially great among women and among people with mental health problems. To take advantage of the full potential of drugs and to avoid drug-related problems, drug prescription needs to be correct and the drugs need to be taken according to the prescribed regimens. LÄS MER

3. 2. Surveys and services : The feasibility of conducting research in Swedish community pharmacies

   Författare :Pia Frisk; Sofia Kälvemark-Sporrong; Margareta Hammarlund-Udenaes; Björn Wettermark; Marcel L Bouvy; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; Community pharmacy; Pharmaceutical services; Drug utilization research; Survey; Patient; Pharmaceutical care; Feasibility; Sweden; Social Pharmacy; Samhällsfarmaci;

   Sammanfattning : For the past decades, there has been a shift in community pharmacy practice from dispensing and compounding towards provision of pharmacy services. Research is important to generate evidence for new services within pharmacy practice. LÄS MER

4. 3. Pharmacometric tools to support translational drug development

   Författare :Rami Ayoun Alsoud; Ulrika S. H. Simonsson; Michael Lyons; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; drug development; pharmacometrics; pharmacokinetics; pharmacodynamics; non-linear mixed effect models; tuberculosis; dose selection; interspecies scaling; pediatric trials; Farmaceutisk vetenskap; Pharmaceutical Science;

   Sammanfattning : The use of model-informed drug development has been shown to save significant costs and improve decision making early in the drug development process. The work in this PhD thesis aimed to employ pharmacometric tools to support translational drug development from the preclinical to the late clinical stages. LÄS MER

5. 4. China's Creation of Biopharmaceutical Drugs : Combining Political Steering, Military Research, and Transnational Networking

   Författare :Åse Linné; Alexandra Waluszewski; Enrico Baraldi; David Ford; Uppsala universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; innovation; biotechnology; China; resource interfaces; commerciali-zation; Chinese government; command network economy; biopharmaceutical drugs; military research;

   Sammanfattning : Not only the Western world is focused on creating new innovations based on scientific discoveries; this is also the case in China where discoveries in biotechnology science are aimed at creating new biopharmaceutical drugs in order to create a future biotechnology industry and in the end generate economic growth. The focus to invest in high-tech industries such as biotechnology can be traced to the “open-door policy” issued in 1978 with the aim to modernize China and transform China into a “socialistic market economy. LÄS MER

7. 5. Real-Time Monitoring of Healthcare Interventions in Routine Care : Effectiveness and Safety of Newly Introduced Medicines

   Författare :Thomas Cars; Johan Sundström; Björn Wettermark; Martin Neovius; Til Stürmer; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Electronic Health Records; Comparative Effectiveness Research; Comparative Safety Research; Sequential drug monitoring; propensity score; real-world data; infliximab; TNF-inhibitors; dronedarone; amiodarone; flecainide; Farmakoepidemiologi; Pharmacoepidemiology;

   Sammanfattning : Before market authorization of new medicines, their efficacy and safety are evaluated using randomized controlled trials. While there is no doubt about the scientific value of randomized trials, they are usually conducted in selected populations with questionable generalizability to routine care. LÄS MER