Sökning: "mir"

Visar resultat 11 - 15 av 163 avhandlingar innehållade ordet mir.

1. 11. Visualization and manipulation of microRNA in neural cells

   Författare :Rohit Sachdeva; Molekylär neurogenetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; miRNA; miR-124; miR-9; embryonic stem cells; neural stem cell; cell transplantation; neurogenesis; microglia;

   Sammanfattning : microRNA (miRNA) are small non-coding RNA, 21-23 nucleotides long. miRNA provide a new layer of regulatory control over gene expression programs. It is increasingly evident that miRNA are cell type and tissue specific. Many miRNAs have been identified to be highly abundant in certain regions of the brain. LÄS MER

3. 12. Effects of Ca2+, microRNAs, and rosuvastatin on insulin-secreting beta cell function

   Författare :Vishal Ashok Salunkhe; Diabetes - öcellsexocytos; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; exocytosis; Ca2 ; miR-375; miR-335; rosuvastatin; voltage-gated Na channels; STXBP1; SNAP25; SYT11; glucose homeostasis; beta cell function;

   Sammanfattning : Type 2 diabetes (T2D) is a condition of high blood glucose levels due to insulin resistance and defective insulin secretion. Impaired insulin secretion plays a major role in the pathophysiology of T2D, it is mainly attributed to beta cell function i.e. failure to secrete insulin or reduced beta cell mass. LÄS MER

4. 13. Continuous-filtering Vernier spectroscopy

   Författare :Chuang Lu; Aleksandra Foltynowicz; Ove Axner; Wei Ren; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; spectroscopy; spectrometer; laser; optical frequency comb; optical cavity; NIR; MIR; flame; robust; time resolution; spectrum; fysik; Physics;

   Sammanfattning : Continuous-filtering Vernier spectroscopy (CF-VS) is a laser-based detection technique that combines the broad spectral coverage of an optical frequency comb (OFC) with the enhanced interaction length provided by an optical cavity. The resonances of the cavity filter the OFC to a small group of comb modes that probe the transitions of the species present in the cavity. LÄS MER

5. 14. Modeling Music : Studies of Music Transcription, Music Perception and Music Production

   Författare :Anders Elowsson; Anders Friberg; Pawel Herman; Anders Askenfelt; Gerhard Widmer; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Music Information Retrieval; MIR; Music; Music Transcription; Music Perception; Music Production; Tempo Estimation; Beat Tracking; Polyphonic Pitch Tracking; Polyphonic Transcription; Music Speed; Music Dynamics; Long-time average spectrum; LTAS; Algorithmic Composition; Deep Layered Learning; Convolutional Neural Networks; Rhythm Tracking; Ensemble Learning; Perceptual Features; Representation Learning;

   Sammanfattning : This dissertation presents ten studies focusing on three important subfields of music information retrieval (MIR): music transcription (Part A), music perception (Part B), and music production (Part C).In Part A, systems capable of transcribing rhythm and polyphonic pitch are described. LÄS MER

7. 15. Vibrio cholerae modulates the immune defense of human gut mucosa

   Författare :Aziz Bitar; Marie-Louise Hammarström; Sun Nynt Wai; Mikael Rehn; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; intestinal epithelial cell; duodenum biopsy; acute cholera; immunomodulation; microRNA; OMV; cytokine; T84 monolayer; miR-146; miR-155; VCC; PrtV; hemolysis; IL-8; TNF-a; IL-1b; IL-18; CCL20; IRAK2; inflammation; mikrobiologi; Microbiology; immunologi; Immunology;

   Sammanfattning : The key function of innate immunity is to sense danger signals and initiate effective responses as a defense mechanism against pathogens. Simultaneously, effector responses must be regulated to avoid excessive inflammation with resulting tissue damage. LÄS MER