Sökning: "acute cholera"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden acute cholera.

  1. 1. Vibrio cholerae modulates the immune defense of human gut mucosa

    Författare :Aziz Bitar; Marie-Louise Hammarström; Sun Nynt Wai; Mikael Rehn; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vibrio cholerae; intestinal epithelial cell; duodenum biopsy; acute cholera; immunomodulation; microRNA; OMV; cytokine; T84 monolayer; miR-146; miR-155; VCC; PrtV; hemolysis; IL-8; TNF-a; IL-1b; IL-18; CCL20; IRAK2; inflammation; mikrobiologi; Microbiology; immunologi; Immunology;

    Sammanfattning : The key function of innate immunity is to sense danger signals and initiate effective responses as a defense mechanism against pathogens. Simultaneously, effector responses must be regulated to avoid excessive inflammation with resulting tissue damage. LÄS MER

  3. 2. Structural and functional studies of the secreted metalloprotease PrtV from Vibrio cholerae

    Författare :Aaron Edwin; Elisabeth Sauer-Eriksson; Helena Berglund; Umeå universitet; []
    Nyckelord :Cholera; Vibrio cholerae; virulence factors; PrtV; X-ray crystallography; NMR;

    Sammanfattning : Cholera, an acute diarrheal diseases caused by the intestinal infection of the pathogenic bacterium Vibrio cholerae, continues to be a global killer in the world today. PrtV, a secreted zinc metalloprotease, is a potent cytotoxic virulence factor of V. cholerae. LÄS MER

  4. 3. Microarray analyses of the small intestinal mucosa during experimental and clinical cholera

    Författare :Carl-Fredrik Flach; Göteborgs universitet; []
    Nyckelord :Vibrio cholerae; cholera toxin; microarray; transporter; intraepithelial lymphocytes; innate defence;

    Sammanfattning : Vibrio cholerae is a Gram-negative bacterium and the causative agent of cholera. The bacteria infect humans via contaminated water and food, and colonize the upper parts of the small intestine to cause disease. The disease is characterized by watery diarrhoea and most of its clinical features can be attributed to the secreted cholera toxin (CT). LÄS MER

  5. 4. Vaccination against cholera and ETEC diarrhea and interventions to improve vaccine immune responses

    Författare :Tanvir Ahmed; Göteborgs universitet; []
    Nyckelord :Vibrio cholerae; ETEC; oral vaccine; CS6; CFA I; Lewis blood group; zinc; breast feeding; T cell; B cell;

    Sammanfattning : Vaccination against cholera and ETEC diarrhea and interventions to improve vaccine immune responses Abstract Vibrio cholerae O1 and enterotoxigenic Escherichia coli (ETEC) together account for the majority of bacterial causes of acute dehydrating diarrhea in children in Bangladesh. Vaccines should be considered as an important public health tool for prevention of these diarrheal diseases. LÄS MER

  7. 5. Vibro cholerae O139 : identification, characterization and vaccine strategies

    Författare :Susanna Falklind Jerkérus; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Vibrio cholerae 0139; diarrhea; detection; carbohydrate mimics;

    Sammanfattning : Cholera is an acute dehydrating diarrheal disease, and epidemics as well as pandemics of cholera are a major health problem in developing countries and cause many deaths each year, especially in children. Cholera is caused by Vibrio cholerae serogroup, 01 and since 1992 also by serogroup 0139. The emergence of V. LÄS MER